Hippocampal mossy fibre boutons as dynamical synapses

• Tipo: Artigo em Livro de Atas de Conferência Internacional
• Data: 2004

Autores

Aguiar, P (Autor) Outra; Willshaw, D (Autor) Outra

Ata de Conferência Internacional

Título: COMPUTATIONAL NEUROSCIENCE: TRENDS IN RESEARCH 2004

Páginas: 699-703

12th Annual Computational Neuroscience Meeting (CNS 03)

Alicante, SPAIN, JUL 05-09, 2003

Indexação

ISI Web of Knowledge - 0 Citações

Scopus - 1 Citação

Outras Informações

ID Authenticus: P-007-E25

DOI: 10.1016/j.neucom.2004.01.116

Abstract (EN): In this work the consequences on the activity of CA3 pyramidal neurons of the dynamic properties (facilitation and depression) associated with hippocampal mossy fibre boutons are explored; namely, a study is carried on the dependence of the pyramidal cell activity with the input stimulus frequency to the mossy fibre boutons as well as the influence of the single vesicle post-synaptic response magnitude on this dependence. We calculate tuning curves for the mossy fibre boutons excitatory post-synaptic potentials as a function of pre-synaptic frequency and we show how this property, together with channels that contribute to spike frequency adaptation, makes the activity of CA3 pyramidal neurons strongly dependent on the temporal patterns of mossy fibres pre-synaptic signals.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 5