Recent advances in the synthesis of xanthones and azaxanthones

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2020

Autores

Resende, DISP (Autor) Outra; Duraes, F (Autor) Outra; Maia, M (Autor) Outra; Emilia Sousa (Autor) FFUP; Pinto, MMM (Autor) Outra

Revista

Título: Organic Chemistry Frontiers

Vol. 7

Páginas: 3027-3066

ISSN: 2052-4110

Editora: Royal Society of Chemistry

Indexação

ISI Web of Knowledge - 16 Citações

Scopus - 16 Citações

Outras Informações

ID Authenticus: P-00S-V2Y

DOI: 10.1039/d0qo00659a

Abstract (EN): Xanthones are importantO-heteroaromatic tricyclic molecules exhibiting a wide range of bioactivities and can represent a showcase to highlight the recent techniques and strategies in organic synthesis towards lead discovery and optimization. This review gives an insight into the recent literature disclosed to obtain the xanthone core, including the drug-like azaxanthones, isosteres of xanthones, by exploiting the optimization of well-known procedures as well as disruptive developed methodologies. With this review, it is expected to provide a useful chemical toolbox to synthetic medicinal chemistry focusing on these privileged structures, covering from 2012 to 2020, with some older examples of azaxanthones.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 40