PDMS-SiO2-TiO2-CaO hybrid materials - Cytocompatibility and nanoscale surface features

• Tipo: Artigo em Revista Científica Internacional
• Data: 2016

Autores

Carlos Almeida, JC (Autor) Outra; Wacha, A (Autor) Outra; Gomes PS (Autor) FMDUP; Fernandes MH (Autor) FMDUP; Helena Vaz Fernandes, MHV (Autor) Outra; Miranda Salvado, IMM (Autor) Outra

Revista

Título: MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS

Vol. 64

Páginas: 74-86

ISSN: 0928-4931

Editora: Elsevier

Indexação

ISI Web of Knowledge - 2 Citações

Scopus - 9 Citações

Outras Informações

ID Authenticus: P-00K-BSK

DOI: 10.1016/j.msec.2016.03.071

Abstract (EN): Two PDMS-SiO2-TiO2-Cao porous hybrid materials were prepared using the same base composition, precursors, and solvents, but following two different sol-gel procedures, based on the authors' previous works where for the first time, in this hybrid system, calcium acetate was used as calcium source. The two different procedures resulted in monolithic materials with different structures, microstructures, and surface wettability. Even though both are highly hydrophobic (contact angles of 127.2 degrees and 150.6 degrees), and present different filling regimes due to different surface topographies, they have demonstrated to be-cytocompatible when tested with human osteoblastic cells, against the accepted idea that high-hydrophobic surfaces are not suitable to cell adhesion and proliferation. At the nanoscale, the existence of hydrophilic silica domains containing calcium, where water molecules are physisorbed, is assumed to support this capability, as discussed.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 13