Second primary gastric cancers in a region with an overall high risk of gastric cancer [Segundos cánceres primarios gástricos en una región con un alto riesgo global de cáncer gástrico]

• Tipo: Artigo em Revista Científica Internacional
• Data: 2020

Autores

Morais, S (Autor) FMUP; Antunes, L (Autor) Outra; Bento, MJ (Autor) Outra; Lunet N (Autor) FMUP

Revista

Título: Gaceta Sanitaria

Vol. 34

Páginas: 393-398

ISSN: 0213-9111

Editora: Elsevier

Indexação

ISI Web of Knowledge - 5 Citações

Scopus - 6 Citações

Outras Informações

ID Authenticus: P-00S-FJF

DOI: 10.1016/j.gaceta.2018.08.010

Abstract (EN): Objective: To compare the incidence rates of gastric cancer among cancer survivors with those in the general population, and estimate the probability of a gastric second primary cancer being diagnosed 10 years after any other first primary cancer. Method: A cohort of first primary cancers (other than gastric) diagnosed in Northern Portugal between 2000 and 2006 (n = 64,648) was followed until 31/12/2012 for gastric second primary cancers. Incidence rates, standardized incidence ratios and the cumulative incidence of gastric second primary cancers were calculated. Results: Overall, 330 patients developed gastric second primary cancers (21.2% within two months). The incidence rate of gastric second primary cancers was higher within two months of the first primary cancer (standardized incidence ratios: 5.20 in males and 7.89 in females), particularly among survivors of cancers of the oesophagus, colon and rectum, than in the remaining period (standardized incidence ratios: 0.64 in males and 0.74 in females). The 10-year risk of a gastric second primary cancer was 0.6% (males: 0.7%; females: 0.4%). Conclusion: The incidence rate of gastric second primary cancers among cancer survivors was higher than in the general population only soon after the first primary cancer, and lower thereafter. Despite the high mortality, the probability of a gastric second primary cancer within 10-years of the first primary cancer was 0.6%. © 2018 SESPAS

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 6