Antithrombotics from the Sea: Polysaccharides and Beyond

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2019

Autores

Carvalhal, F (Autor) Outra; Cristelo, RR (Autor) Outra; Resende, DISP (Autor) Outra; Pinto, MMM (Autor) Outra; Emilia Sousa (Autor) FFUP; Marta Correia da Silva (Autor) FFUP

Revista

Título: Marine Drugs

Vol. 17

Página Final: 170

ISSN: 1660-3397

Editora: MDPI

Indexação

ISI Web of Knowledge - 19 Citações

Scopus - 19 Citações

Outras Informações

ID Authenticus: P-00Q-CTK

DOI: 10.3390/md17030170

Abstract (EN): Marine organisms exhibit some advantages as a renewable source of potential drugs, far beyond chemotherapics. Particularly, the number of marine natural products with antithrombotic activity has increased in the last few years, and reports show a wide diversity in scaffolds, beyond the polysaccharide framework. While there are several reviews highlighting the anticoagulant and antithrombotic activities of marine-derived sulfated polysaccharides, reports including other molecules are sparse. Therefore, the present paper provides an update of the recent progress in marine-derived sulfated polysaccharides and quotes other scaffolds that are being considered for investigation due to their antithrombotic effect.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 31