Staphylococcus aureus Toxins and Their Molecular Activity in Infectious Diseases

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2018

Autores

Diana Oliveira (Autor) FEUP; Anabela Borges (Autor) FEUP; Manuel Simões (Autor) FEUP

Revista

Título: Toxins

Nº de Série 6 Vol. 10 Nº 252

Páginas: 1-252

ISSN: 2072-6651

Editora: MDPI

Indexação

ISI Web of Knowledge - 18 Citações

ISI Web of Science

Scopus - 241 Citações

Projetos Associados

LEPABE - Laboratório de Engenharia de Processos, Ambiente, Biotecnologia e Energia

LEPABE-2-ECO-INNOVATION - LEPABE-2-ECO-INNOVATION

Outras Informações

ID Authenticus: P-00P-0QE

DOI: 10.3390/toxins10060252

Abstract (EN): Staphylococcus aureus is a microorganism resident in the skin and nasal membranes with a dreadful pathogenic potential to cause a variety of community and hospital-acquired infections. The frequency of these infections is increasing and their treatment is becoming more difficult. The ability of S. aureus to form biofilms and the emergence of multidrug-resistant strains are the main reasons determining the challenge in dealing with these infections. S. aureus' infectious capacity and its success as a pathogen is related to the expression of virulence factors, among which the production of a wide variety of toxins is highlighted. For this reason, a better understanding of S. aureus toxins is needed to enable the development of new strategies to reduce their production and consequently improve therapeutic approaches. This review focuses on understanding the toxin-based pathogenesis of S. aureus and their role on infectious diseases.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 19