Wound-Healing Peptides for Treatment of Chronic Diabetic Foot Ulcers and Other Infected Skin Injuries

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2017

Autores

Gomes, A (Autor) Outra; Catia Teixeira (Autor) FCUP; Ferraz, R (Autor) Outra; Prudencio, C (Autor) Outra; Paula Gomes (Autor) FCUP

Revista

Título: Molecules

Vol. 22 Nº 2

Página Final: 1743

ISSN: 1420-3049

Editora: MDPI

Indexação

ISI Web of Knowledge - 91 Citações

Scopus - 91 Citações

Outras Informações

ID Authenticus: P-00N-6SW

DOI: 10.3390/molecules22101743

Abstract (EN): As the incidence of diabetes continues to increase in the western world, the prevalence of chronic wounds related to this condition continues to be a major focus of wound care research. Additionally, over 50% of chronic wounds exhibit signs and symptoms that are consistent with localized bacterial biofilms underlying severe infections that contribute to tissue destruction, delayed wound-healing and other serious complications. Most current biomedical approaches for advanced wound care aim at providing antimicrobial protection to the open wound together with a matrix scaffold (often collagen-based) to boost reestablishment of the skin tissue. Therefore, the present review is focused on the efforts that have been made over the past years to find peptides possessing wound-healing properties, towards the development of new and effective wound care treatments for diabetic foot ulcers and other skin and soft tissue infections.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 18