Heterocyclic Antioxidants in Nature: Coumarins

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2017

Autores

Matos, MJ (Autor) Outra; Vazquez Rodriguez, S (Autor) Outra; Fonseca, A (Autor) Outra; Uriarte, E (Autor) Outra; Santana, L (Autor) Outra; Fernanda Borges (Autor) FCUP

Revista

Título: Current Organic Chemistry

Vol. 21

Páginas: 311-324

ISSN: 1385-2728

Editora: Bentham Science

Indexação

ISI Web of Knowledge - 40 Citações

Scopus - 42 Citações

Outras Informações

ID Authenticus: P-00M-E8M

DOI: 10.2174/1385272820666161017170652

Abstract (EN): Coumarins represent an important family of naturally occurring and/or synthetic oxygen- containing heterocycles, bearing a characteristic benzopyrone framework. These compounds are widely distributed both in human diet and therapeutics. Among other characteristics, several coumarin derivatives proved to have an interesting antioxidant profile. In the current review, an overview of the role of natural coumarins as important antioxidants is presented and discussed. The benefits of antioxidants to prevent chronic diseases is also discussed in the current review. The most common assays performed to evaluate the antioxidant capacity described in this review are related to different reactive oxygen species involved in the oxidative process. Several reaction mechanisms were studied to investigate the antioxidant profile of coumarins. Among them, hydrogen atom transfer (HAT) and single electron transfer transfer (SET), were highly cited. To make the organization of this overview as clear as possible, coumarin derivatives were dived in: simple coumarins; aliphatic, terpenoid and aromaticcontaining coumarins; ring- fused coumarins and ellagic acid derivatives.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 14