Bioactive Coumarins from Marine Sources: Origin, Structural Features and Pharmacological Properties

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2015

Autores

Vazquez Rodriguez, S (Autor) Outra; Matos, MJ (Autor) Outra; Fernanda Borges (Autor) FCUP; Uriarte, E (Autor) Outra; Santana, L (Autor) Outra

Revista

Título: Current Topics in Medicinal Chemistry

Vol. 15

Páginas: 1755-1766

ISSN: 1568-0266

Editora: Bentham Science

Indexação

ISI Web of Knowledge - 19 Citações

Scopus - 22 Citações

Outras Informações

ID Authenticus: P-00G-BB6

DOI: 10.2174/1568026615666150427125916

Abstract (EN): Nature is an ancient pharmacy that is largely used as an inspiring source for drug discovery processes for the early eras. Several drugs used nowadays are of natural product origin or inspired on the basis of natural product structures and approximately half of the 20 best-selling non-protein drugs are related to natural products. However, a largely unexplored marine world that presumably harbors the most biodiversity may be the vastest resource to discover compounds with remarkable biological properties. Marine based drug discovery research has been mainly focused on crude extracts. The purpose of this review is to summarize the findings reported in this area, particularly focuses on marine-derived coumarincontaining compounds.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 12