Tetracycline, oxytetracycline and chlortetracycline determination by flow injection potentiometry

• Tipo: Artigo em Revista Científica Internacional
• Data: 1998

Autores

Couto, CMCM (Autor) Outra; Lima, JLFC (Autor) FFUP; Conceicao, M (Autor) FFUP; Montenegro, BSM (Autor) Outra; Reis, S (Autor) FFUP

Revista

Título: Journal of Pharmaceutical and Biomedical Analysis

Vol. 18

Páginas: 527-533

ISSN: 0731-7085

Editora: Elsevier

Indexação

ISI Web of Knowledge - 29 Citações

Scopus - 28 Citações

Classificação Científica

FOS: Ciências exactas e naturais > Química

Outras Informações

ID Authenticus: P-001-6NM

DOI: 10.1016/s0731-7085(98)00207-6

Abstract (EN): This paper describes tetracycline (TCH), oxytetracycline (OTCH) and chlortetracycline (CTCH) determination by flow injection potentiometry. In the flow system proposed TC samples are inserted in a carrier solution and converged with a Cu(II) solution of known concentration; the Cu(II) decrease due to its complexation with tetracyclines (TC) was monitored. The detector used was a homogeneous crystalline CuS/Ag2S double membrane tubular electrode with increased sensitivity. The present system allows tetracyclines determinations within a 48.1-4.8 x 10(3) ppm for TCH, 49.1-4.9 x 10(3) ppm for OTCH and 51.5-5.1 x 10(3) ppm for CTCH and a precision better than 0.4% for the three TC species. This procedure accomplishes 150-200 samples h(-1) with a Cu(II) consumption of about 13 mu g determination(-1).

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 7