Biodegradation of sulfamethoxazole and other sulfonamides by Achromobacter denitrificans PR1

• Tipo: Artigo em Revista Científica Internacional
• Data: 2014

Autores

Patrícia J. M. Reis (Autor) FEUP; Ana C. Reis (Autor) FEUP; Benjamin Ricken (Autor) Outra; Boris A. Kolvenbach (Autor) Outra; Célia M. Manaia (Autor) Outra; Philippe F. X. Corvini (Autor) Outra; Olga C. Nunes (Autor) FEUP

Revista

Título: Journal of Hazardous Materials

Vol. 280

Páginas: 741-749

ISSN: 0304-3894

Editora: Elsevier

Indexação

ISI Web of Knowledge - 61 Citações

Scopus - 106 Citações

Classificação Científica

FOS: Ciências da engenharia e tecnologias > Engenharia civil

Projetos Associados

PTDC/AAC-AMB/113091/2009 - Eliminação de micropoluentes com actividade antimicrobiana de águas residuais

Outras Informações

ID Authenticus: P-009-WHB

DOI: 10.1016/j.jhazmat.2014.08.039

Abstract (EN): This study aimed to isolate and characterize a microbial culture able to degrade sulfonamides. Sulfamethoxazole (SMX)-degrading microorganisms were enriched from activated sludge and wastewater. The resultant mixed culture was composed of four bacterial strains, out of which only Achromobacter denitrificans PR1 could degrade SMX. This sulfonamide was used as sole source of carbon, nitrogen and energy with stoichiometric accumulation of 3-amino-5-methylisoxazole. Strain PR1 was able to remove SMX at a rate of 73.6 +/- 9.6 mu mol(SMX)/g(cell) (dry) (weight) h. This rate more than doubled when a supplement of amino acids or the other members of the mixed culture were added. Besides SMX, strain PR1 was able to degrade other sulfonamides with anti-microbial activity. Other environmental Achromobacter spp. could not degrade SMX, suggesting that this property is not broadly distributed in members of this genus. Further studies are needed to shed additional light on the genetics and enzymology of this process.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 9