Pharmacogenomics and Molecular Epidemiology II

Code:

PDMOM13_8

Acronym:

PDMOM13_8

Keywords
Classification	Keyword
OFICIAL	Medicine

Instance: 2020/2021 - SP (of 01-09-2020 to 31-07-2021)

Active?	Yes
Responsible unit:	Departamento de Patologia
Course/CS Responsible:	Molecular Medicine and Oncology

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
PDBM	0	Current Studies Plan	1	-	3	14	81
PDMOM	3	Current Studies Plan	1	-	3	14	81

Teaching language

Suitable for English-speaking students

Objectives

The objective of the course is to gain knowledge of the principal updated knowledge on Pharmacogenomics and Personalized Medicne. A particular focus will be given to the new biomarkers that may be in association to mechanisms of disease and to tailored therapeutic approaches. A focus will be given  Ecogenetics and Molecular Epidemiology indicating its importance to Pharmacogenomics. It is aimed to improve the student s evaluation skills to discuss the introduction of new Biomarkers as Predictive factores of the response to treament or as prognostic factors. The purpose of the course is also to prepare students to become leaders in this scientific field.

Learning outcomes and competences

Students should be able to recognize the updated information regarding Pharmacogenomics and its  importance in the correct management of disease. They have to be able to do their intervention at the level of information and delivery of medication and on Public Health towards health education. In this sense the study of cases with different clinical relevance to humans, as focused in the syllabus, will prepare the students for this professional challenge. Furthermore, the intervention of a Health Sciences professional must include the knowledge of properly collect and manage the samples according to the best of knowledge, including a correct interpretation of the results.

Working method

Presencial

Program

-Introduction to Pharmacogenomics: on the route from Molecular Biology to Personalized Medicine

- Integrative Epidemiology: From Risk Assessment to Outcome Prediction

- Biopathology and Molecular Medicine

- Pharmacokinetics and Pharmacodynamics

- Biotransformation and Phase I and II Metabolism

- Genetic Polymorphisms and Pharmacogenomics

- Phase I Metabolism and Genetic Polymorphisms

- Phase II Metabolism Genetic Polymorphisms

- Other Genetic Models in Pharmacogenomics

- Pharmacogenomics in Preventive Medicine

- Primer in Medical treatment in Oncology

- Pharmacogenomics in Oncology

- Pharmacogenomics and Other Pathologies

- Pharmacogenomics and the development of new therapeutic targets

- Therapeutic and prognostic models: implications for pharmacogenomics (

- Vírus, Molecular Epidemiology and Therapeutic Strategies

- Pharmacogenomics and Biomedical Sciences
- Clinical Research, personalized medicine and precision medicine

Mandatory literature

Yui-Wing Francis Lam Larisa Cavallari; Pharmacogenomics

Teaching methods and learning activities

Lecture and discussion of relevant theoretical concepts in the classroom, self-study orientation of students by consulting annotated bibliography.
Seminars Brainstorm on pertinent issues related to the matter lectured in the classroom. Essays writing and presentation, an Project Evaluation as part of the continuous assessment.

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Designation	Weight (%)
Exame	75,00
Participação presencial	25,00
Total:	100,00

Amount of time allocated to each course unit

Designation	Time (hours)
Estudo autónomo	67,00
Frequência das aulas	14,00
Total:	81,00

Eligibility for exams

At least 75% of presences in class.

Calculation formula of final grade

Without formula