Clinical Research - Diagnostic studies

Code:

OPT68

Acronym:

IC-ED

Keywords
Classification	Keyword
OFICIAL	Medicine

Instance: 2017/2018 - 1S

Active?	Yes
Responsible unit:	Department of Community Medicine, Information and Health Decision Sciences
Course/CS Responsible:	Integrated Master in Medicine

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MIMED	0	Mestrado Integrado em Medicina- Plano oficial 2013 (Reforma Curricular)	4	-	1,5	14	40,5

Teaching language

Suitable for English-speaking students

Objectives

This curricular unit aims to develop the theoretical and practical foundations necessary for the interpretation of results, design and implementation of diagnostic studies in clinical research, as questions about the process, tests and technologies applied to diagnosis.

Learning outcomes and competences

At the end of this curricular unit students should be able to: define reproducibility measures and validity of diagnosis studies; discuss the operational characteristics of the diagnosis studies; use measures of validity; design studies for diagnosis tests assessment; critically analyze studies.

Working method

Presencial

Program

Measurement in research and diagnosis in medicine. Definition of reproducibility and validity. Reproducibility measures (agreement proportions, kappa statistics and proportions of specific agreement). Validity measures (sensitivity, specificity, likelihood ratios, probabilities and Bayes’ theorem, predictive values and ROC curves). Multiple tests. Design of studies. Quality of studies and levels of evidences. Validation and cost-benefit. Integration in decision. Screening tests.

Mandatory literature

Riegelman, R.K. ; Studying A Study and Testing a Test: Reading Evidence-based Health Research Studying A Study and Testing a Test: Reading Evidence-based Health Research (6th Edition), Philadelphia: Lippincott Williams & Wilkins , 2012

Teaching methods and learning activities

After the presentation of each topic there will be time for group discussion and analysis of scientific articles published in the medical literature, as well as resolution of individual exercises. An e-learning platform will be used to deliver class notes and to facilitate the communication between students and teaching staff.

Evaluation Type

Distributed evaluation without final exam

Assessment Components

Designation	Weight (%)
Participação presencial	25,00
Trabalho escrito	75,00
Total:	100,00

Calculation formula of final grade

Final grade will be based on continuous evaluation of clinical skills and knowledge (25%) and the individual task (75%).