Metabolic syndrome, physical activity and cardiac autonomic function

• Type: Article in International Scientific Journal
• Date: 2012

Authors

soares-miranda, l (Author) Other; sandercock, g (Author) Other; vale, s (Author) Other; santos, r (Author) Other; abreu, s (Author) Other; moreira, c (Author) Other; mota, j (Author) FADEUP

Journal

Title: Diabetes/Metabolism Research and Reviews

Vol. 28

Pages: 363-369

ISSN: 1520-7552

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 32 Citations

Scopus - 19 Citations

Scientific classification

FOS: Medical and Health sciences > Clinical medicine

Other information

Authenticus ID: P-002-AHV

DOI: 10.1002/dmrr.2281

Abstract (EN): Background Our primary aim was to investigate the associations that components of metabolic syndrome and physical activity have with cardiac autonomic nervous system activity as estimated by heart rate variability (HRV) in young adults free of metabolic abnormalities. We also aimed to identify predictors of 3-year changes in HRV. Methods Physical activity was assessed annually in 163 healthy participants over 3?years (20082010). Components of metabolic syndrome measured annually were; waist circumference, systolic blood pressure, high-density lipoprotein, triglycerides, glucose, and C-reactive protein. A linear mixed regression model was used to assess associations between HRV, metabolic syndrome components and physical activity. Linear regression was used to identify predictors of changes in HRV. Results ?Metabolic syndrome components were negatively associated with HRV indices and higher heart rate, while physical activity was associated with higher HRV and lower heart rate. Physical activity and inflammation were predictors of positive and negative changes in HRV indices, respectively. Conclusions ?In participants without significant metabolic abnormalities, metabolic syndrome components were still associated with less favourable HRV profiles. Physical activity and inflammation were both able to predict changes in HRV, albeit in different directions. It appears that the process of autonomic dysfunction starts at a young age and may be mediated in part by inflammation. Metabolic syndrome prevalence is increasing in younger populations; promoting the metabolic and autonomic benefits of exercise remains imperative. Copyright (C) 2012 John Wiley & Sons, Ltd.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7