Vibrational Spectroscopy Studies on Biologically Relevant Molecules: From Anticancer Agents to Drugs of Abuse

• Type: Chapter or Part of a Book
• Date: 2007

Authors

Marques, MPM (Author) Other; Borges, F (Author) FFUP; Amorim da Costa, AMA (Author) Other; Batista de Carvalho, LAEB (Author) Other

Book

Title: New Approaches in Biomedical Spectroscopy

Indexing

ISI Web of Knowledge - 1 Citation

Scopus - 2 Citations

Scientific classification

FOS: Natural sciences > Chemical sciences

CORDIS: Physical sciences > Chemistry > Applied chemistry

Other information

Authenticus ID: P-004-E11

Abstract (EN): Vibrational spectroscopy (both Raman and Inelastic Neutron Scattering), coupled to quantum mechanical calculations, is used in order to perform a thorough analysis of several biologically relevant molecules, such as chemotherapeutic agents, biogenic polyamines and their metal chelates, cardiovascular protectors, non-steroid anti-inflammatory drugs (NSAID's), drugs of abuse and phenolic compounds. The conjugation of these techniques yields valuable information regarding the structural preferences of the systems under investigation, which may help establish the structure-activity relationships (SAR's) ruling their biological function.

Language: English

Type (Professor's evaluation): Scientific