Go to:
Logótipo
Você está em: Start » Publications » View » PRIMACENES: novel non-cytotoxic primaquine-ferrocene conjugates with anti-Pneumocystis carinii activity
Publication

PRIMACENES: novel non-cytotoxic primaquine-ferrocene conjugates with anti-Pneumocystis carinii activity

Title
PRIMACENES: novel non-cytotoxic primaquine-ferrocene conjugates with anti-Pneumocystis carinii activity
Type
Article in International Scientific Journal
Year
2010
Authors
Joana Matos
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Nuno Vale
(Author)
FCUP
View Personal Page Send message Search for Participant Publications View Authenticus page View ORCID page
Margaret S Collins
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Jiri Gut
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Philip J Rosenthal
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Melanie T Cushion
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Rui Moreira
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Paula Gomes
(Author)
FCUP
View Personal Page You do not have permissions to view the institutional email. Search for Participant Publications View Authenticus page View ORCID page
Journal
Title: MedChemCommImported from Authenticus Search for Journal Publications
Vol. 1
Pages: 199-201
ISSN: 2040-2503
Scientific classification
FOS: Natural sciences > Chemical sciences
Other information
Authenticus ID: P-003-3PK
Abstract (EN): Primacenes, novel ferrocene-primaquine conjugates, were synthesized and screened for their antimalarial and anti-pneumocystis activity. Primacenes obtained by coupling primaquine amino acid derivatives to ferrocenoic acid were significantly active against Pneumocystis carinii and devoid of cytotoxicity, thus being more selective than the parent drug.
Language: English
Type (Professor's evaluation): Scientific
License type: Click to view license CC BY-NC
Documents
File name Description Size
ART_53 128.06 KB
Related Publications

Of the same authors

Imidazoquines as Antimalarial and Antipneumocystis Agents (2009)
Article in International Scientific Journal
Nuno Vale; Miguel Prudencio; Catarina A Marques; Margaret S Collins; Jiri Gut; Fatima Nogueira; Joana Matos; Philip J Rosenthal; Melanie T Cushion; Virgilio E do Rosario; Maria M Mota; Rui Moreira; Paula Gomes

Of the same scientific areas

1D and 2D nanomaterials as building blocks for 3D composites: surfactant-mediated assembly, characterization and electrocatalytic studies (2021)
Thesis
Bárbara Catarina Abreu Teixeira de Brito e Faro
Valorisation of by-products from brewing and canned fish industry: characterization of hydrolysates with antihypertensive and antioxidant activities (2016)
Thesis
Elsa Marisa Ferreira Vieira
Understanding the hFAS Enzyme - a Promising Anticancer Target (2022)
Thesis
Pedro Miguel Coelho Paiva
Understanding and Optimizing Extremozymes for Industrial Processes (2022)
Thesis
Matilde de Freitas Ribeiro Viegas
Traceability of genetically modified organisms in the food chain: Development of biosensing devices as new approaches for their detection (2018)
Thesis
Alexandra Patrícia Rego Plácido do Nascimento

See all (2508)

Of the same journal

3-Substituted coumarins as dual inhibitors of AChE and MAO for the treatment of Alzheimer's disease (2012)
Article in International Scientific Journal
Viña, D; Matos, MJ; Yáñez, M; Santana, L; Uriarte, E
Synthesis of coumarin-chalcone hybrids and evaluation of their antioxidant and trypanocidal properties (2013)
Article in International Scientific Journal
Vazquez Rodriguez, S; Figueroa Guíñez, R; Matos, MJ; Santana, L; Uriarte, E; Lapier, M; Maya, JD; Olea Azar, C
Progress in the development of small molecules as new human A(3) adenosine receptor ligands based on the 3-thiophenylcoumarin core (2016)
Article in International Scientific Journal
Klotz, KN; Fernanda Borges; Matos, MJ; Vilar, S; Kachler, S; Vazquez Rodriguez, S; Varela, C; Delogu, G; Hripcsak, G; Santana, L; Uriarte, E
PRIMACINS, N-cinnamoyl-primaquine conjugates, with improved liver-stage antimalarial activity (2012)
Article in International Scientific Journal
Bianca Perez; Catia Teixeira; Ines S Albuquerque; Jiri Gut; Philip J Rosenthal; Miguel Prudencio; Paula Gomes
MAO inhibitory activity of bromo-2phenylbenzofurans: synthesis, in vitro study, and docking calculations (2017)
Article in International Scientific Journal
Delogu, GL; Pintus, F; Mayan, L; Matos, MJ; Vilar, S; Munin, J; Fontenla, JA; Hripcsak, G; Fernanda Borges; Vina, D

See all (9)

Recommend this page Top
Copyright 1996-2024 © Faculdade de Medicina da Universidade do Porto  I Terms and Conditions  I Acessibility  I Index A-Z  I Guest Book
Page created on: 2024-10-05 at 23:48:38
Acceptable Use Policy | Data Protection Policy | Complaint Portal | Política de Captação e Difusão da Imagem Pessoal em Suporte Digital