Suspicious for Malignancy

• Type: Chapter or Part of a Book
• Date: 2023

Authors

Fernando Schmitt (Author) FMUP; Chandra, A (Author) Other; Filie, A (Author) Other; Lai, C (Author) Other

Book

Title: The Bethesda System for Reporting Thyroid Cytopathology: Definitions, Criteria, and Explanatory Notes, Third Edition

Pages: 117-134

ISBN: 978-303128046-7; 978-303128045-0

Publisher: Springer Nature

Indexing

Scopus - 0 Citations

Other information

Authenticus ID: P-00Z-4T6

DOI: 10.1007/978-3-031-28046-7_7

Abstract (EN): The term ¿Suspicious For Malignancy¿ (SFM) is applied when the cytologic features of a thyroid fine needle aspiration are worrisome for papillary thyroid carcinoma, medullary thyroid carcinoma, lymphoma, or other malignant neoplasm but are quantitatively and/or qualitatively insufficient for a definitive diagnosis. Reasons for diagnostic uncertainty include suboptimal sampling or cellular preservation, an unusual tumor variant, overlapping cytomorphologic features with other thyroid lesions, or inability to perform immunophenotyping for lymphoma. Although the proportion varies among laboratories, approximately 3% of thyroid fine needle aspirations are reported as SFM. SFM is a heterogeneous category because it includes a variety of different malignancies, but most cases are suspicious for papillary thyroid carcinoma. As with any indeterminate diagnosis, this category should be used judiciously so that patients are managed as appropriately as possible. Usual management is either lobectomy or near total thyroidectomy. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 17