Segmentation of the carotid intima-media region in B-mode ultrasound images

• Type: Article in International Scientific Journal
• Date: 2010

Authors

Rui Rocha (Author) FEUP; Aurélio Campilho (Author) FEUP; Jorge Silva (Author) FEUP; Elsa Azevedo (Author) Other; Rosa Santos (Author) Other

Journal

Title: Image and Vision Computing

Vol. 28

Pages: 614-625

ISSN: 0262-8856

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 67 Citations

ISI Web of Science

Scopus - 75 Citations

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Other information

Authenticus ID: P-003-7TE

DOI: 10.1016/j.imavis.2009.09.017

Abstract (EN): This paper proposes a new approach for the segmentation of both near-end and far-end intima-media regions of the common carotid artery in ultrasound images. The method requires minimal user interaction and is able to segment the near-end wall in arteries with large, hypoechogenic and irregular plaques, issues usually not considered previously due to the increased segmentation difficulty. The adventitia is detected by searching for the best fit of a cubic spline to edges having features compatible with the adventitia boundary. The algorithm uses a global smoothness constraint and integrates discriminating features of the adventitia to reduce the attraction by other edges. Afterwards, using the information of the adventitia location, the lumen boundary is detected by combining dynamic programming, smooth intensity thresholding surfaces and geometric snakes. Smooth contours that correctly adapt to the intima are produced, even in the presence of deep concavities. Moreover, unlike balloon-based snakes, the propagation force does not depend on gradients and does not require a predefined direction. An extensive statistical evaluation is computed, using a set of 47 images from 24 different symptomatic patients, including several classes, sizes and shapes of plaques. Bland-Altman plots of the mean intima-media thickness, for manual segmentations of two medical experts, show a high intra-observer and inter-observer agreement, with mean differences close to zero (mean between -0.10 mm and 0.18 mm) and with the large majority of differences within the limits of agreement (standard deviation between 0.10 mm and 0.12 mm). Similar Plots reveal it good agreement between the automatic and the manual segmentations (mean between -0.07 mm and 0.11 mm and standard deviation between 0.11 mm and 0.12 mm).

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 12