Microbiota Modulation in Patients with Metabolic Syndrome

• Type: Another Publication in an International Scientific Journal
• Date: 2022

Authors

Araujo, R (Author) Other; Borges-Canha, M (Author) FMUP; Pedro Pimentel-Nunes (Author) FMUP

Journal

Title: Nutrients

Vol. 14

ISSN: 2072-6643

Publisher: MDPI

Indexing

ISI Web of Knowledge - 0 Citations

Scopus

Other information

Authenticus ID: P-00X-GRG

DOI: 10.3390/nu14214490

Abstract (EN): Metabolic syndrome (MS) comprises a vast range of metabolic dysfunctions, which can be associated to cardiovascular disease risk factors. MS is reaching pandemic levels worldwide and it currently affects around 25% in the adult population of developed countries. The definition states for the diagnosis of MS may be clear, but it is also relevant to interpret the patient data and realize whether similar criteria were used by different clinicians. The different criteria explain, at least in part, the controversies on the theme. Several studies are presently focusing on the microbiota changes according to the components of MS. It is widely accepted that the gut microbiota is a regulator of metabolic homeostasis, being the gut microbiome in MS described as dysbiotic and certain taxonomic groups associated to metabolic changes. Probiotics, and more recently synbiotics, arise as promising therapeutic alternatives that can mitigate some metabolic disturbances, namely by correcting the microbiome and bringing homeostasis to the gut. The most recent studies were revised and the promising results and perspectives revealed in this review.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 13