Metabolic Effects of an Oral Glucose Tolerance Test Compared to the Mixed Meal Tolerance Tests: A Narrative Review

• Type: Another Publication in an International Scientific Journal
• Date: 2022

Authors

Lages, M (Author) Other; Barros, Renata (Author) FCNAUP; Moreira, Pedro (Author) FCNAUP; Guarino, MP (Author) Other

Journal

Title: Nutrients

Vol. 74

Final page: 2032

ISSN: 2072-6643

Publisher: MDPI

Indexing

ISI Web of Knowledge - 3 Citations

Scientific classification

CORDIS: Health sciences

FOS: Medical and Health sciences

Other information

Authenticus ID: P-00W-HWB

DOI: 10.3390/nu14102032

Abstract (EN): The oral glucose tolerance test (OGTT) is recommended for assessing abnormalities in glucose homeostasis. Recognised as the gold standard test for diagnosing diabetes, the OGTT provides useful information about glucose tolerance. However, it does not replicate the process of absorption and digestion of complex foods, such as that which occurs with a mixed meal tolerance test (MMTT), an alternative that is still not well explored in the diagnosis of metabolic alterations. The MMTT could be an asset in detecting glucose homeostasis disorders, including diabetes since it has more similarities to the common dietary pattern, allowing early detection of subtle changes in metabolic homeostasis in response to combined nutrients. This alternative has the advantage of being more tolerable and pleasant to patients since it induces a more gradual increase in blood glucose, thus reducing the risk of rebound hypoglycemia and other related complications. The present article reviewed the clinical data available regarding the possibility of screening or diagnosing altered glucose homeostasis, including type 2 diabetes mellitus, with the MMTT.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 15