Data supporting the shedding of larger extracellular vesicles by multidrug resistant tumour cells

• Type: Article in International Scientific Journal
• Date: 2016

Authors

Lopes Rodrigues, V (Author) Other; Di Luca, A (Author) Other; Sousa, D (Author) Other; Seca, H (Author) Other; Meleady, P (Author) Other; Henry, M (Author) Other; Lima, RT (Author) Other; O'Connor, R (Author) Other; Helena Vasconcelos, MH (Author) FFUP

Journal

Title: Data in Brief

Vol. 6

Pages: 1023-1027

ISSN: 2352-3409

Publisher: Elsevier

Indexing

Scopus - 6 Citations

Other information

Authenticus ID: P-00K-5T7

DOI: 10.1016/j.dib.2016.02.004

Abstract (EN): To date, there are no simple and minimally invasive methods to diagnose MDR. Extracellular vesicles (EVs) are shed by all cells, carry a specific cargo from the donor cells and are present in several body fluids, which means that they can potentially be easily collected from cancer patients and become the source of biomarkers to diagnose cancer. This data article contains a full list of the proteins identified in the EVs shed by an isogenic pair of chronic myeloid leukaemia cells (MDR cells and their drug-sensitive counterparts) by LC/MS/MS analysis, together with their GeneOntology analysis. In addition, it also contains data from protein content analysis and Dynamic light scattering count-rate events of the referred EVs as well as of the EVs shed from an isogenic pair of non-small cell lung cancer cells (MDR cells and their drug-sensitive counterparts). The interpretation of the data presented in this article and further extensive insights can be found in "Multidrug resistant tumour cells shed more microvesicles-like EVs and less exosomes than their drug-sensitive counterpart cells" [1]. © 2016 The Authors.

Language: English

Type (Professor's evaluation): Scientific