Production, properties, and applications of solid self-emulsifying delivery systems (S-SEDS) in the food and pharmaceutical industries

• Type: Article in International Scientific Journal
• Date: 2018

Authors

Antónia Gonçalves (Author) Other; Nooshin Nikmaram (Author) Other; Shahin Roohinejad (Author) Other; Berta N. Estevinho (Author) FEUP; Fernando Rocha (Author) FEUP; Ralf Greiner (Author) Other; David Julian McClement (Author) Other

Journal

Title: Colloids and Surfaces A: Physicochemical and Engineering Aspects

Vol. 538

Pages: 108-126

ISSN: 0927-7757

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 6 Citations

ISI Web of Science

Scopus - 24 Citations

Associated Projects

LEPABE - Laboratório de Engenharia de Processos, Ambiente, Biotecnologia e Energia

LEPABE-2-ECO-INNOVATION - LEPABE-2-ECO-INNOVATION

Other information

Authenticus ID: P-00N-6MQ

DOI: 10.1016/j.colsurfa.2017.10.076

Abstract (EN): The food and pharmaceutical industries aim to develop innovative delivery systems to meet the increasing consumer demand for healthier and safer food products and to improve the efficacy of drug formulations, respectively. Many bioactive agents with beneficial physiological and pharmacological activities are difficult to deliver because of their poor water solubility, chemical instability, or low oral bioavailability. Nano- and micro-encapsulation technologies are therefore being developed to overcome these limitations. This review article provides an overview of several lipid-based carriers suitable for the encapsulation of nutraceutical and pharmaceutical molecules, including their structures, constituents, production methods, and applications. It then focuses on the preparation, characterization, and application of solid self-micro-emulsifying delivery system (S-SMEDS). Finally, potential challenges of using S-SMEDS and S-SNEDS as delivery systems in the food and pharmaceutical industries are addressed.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 19