Nonlinear controller for bispectral index tracking: Robustness and on-line retuning

• Type: Article in International Scientific Journal
• Date: 2017-01-31

Authors

Nogueira, F (Author) Other; Mendonca, T (Author) FCUP; Rocha, P (Author) FEUP

Journal

Title: Control Engineering Practice

Vol. 58

Pages: 343-353

ISSN: 0967-0661

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 2 Citations

ISI Web of Science

Scopus - 2 Citations

Other information

Authenticus ID: P-00M-B3N

DOI: 10.1016/j.conengprac.2016.03.021

Abstract (EN): In this paper, the performance of a control law designed for the automatic administration of propofol and of remifentanil in order to track a desired level for the bispectral index (BIS), used as a measure of the depth of anesthesia, is analyzed under the presence of model parameters uncertainties. It is theoretically proved and illustrated by simulations that under these circumstances the controller has a very good performance as the BIS converges to a value contained in a neighborhood of the desired BIS level. A retuning strategy in order to improve the BIS tracking under the presence of uncertainties was also theoretically deduced. Simulations show that this strategy leads to BIS tracking improvement. The performance of the controller in clinical environment is illustrated by a clinical case.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 11