Phytochemical investigations and biological potential screening with cellular and non-cellular models of globe amaranth (Gomphrena globosaL.) inflorescences

• Type: Article in International Scientific Journal
• Date: 2012

Authors

Luis R Silva (Author) Other; Patricia Valentao (Author) FFUP; Joana Faria (Author) Other; Federico Ferreres (Author) Other; Carla Sousa (Author) FFUP; Angel Gil Izquierdo (Author) Other; Brigida R Pinho (Author) Other; Paula B Andrade (Author) FFUP

Journal

Title: Food Chemistry

Vol. 135 No. 3

Pages: 756-763

ISSN: 0308-8146

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 16 Citations

Scopus - 28 Citations

Scientific classification

FOS: Agrarian Sciences > Other Agrarian Sciences

Other information

Authenticus ID: P-002-3EC

DOI: 10.1016/j.foodchem.2012.05.015

Abstract (EN): Gomphrena globosaL. is a popular edible plant used as food colourant and in traditional medicine. In this work, 24 phenolic compounds and eight betacyanins were determined by HPLC-DAD in three different extracts of G. globosa inflorescences. The decoction presented the highest amount of phenolic compounds, kaempferol-3-O-(6-rhamnosyl)hexoside plus kaempferol-3-O-hexoside being the main compounds. The rich betacyanins extract showed isogomphrenin III and gomphrenin III as major metabolites. Decreases in the nitric oxide amounts were observed in LPS-stimulated RAW 264.7 cells. In vitro scavenging micro assays against several reactive species revealed a great antioxidant capacity, particularly against superoxide radical. In general, the best results were obtained with decoction. Some relationships between activity and composition were established. The data provide evidence of the G. globosa inflorescences potential as a source of anti-inflammatory compounds, with relevance for the treatment of acute or chronic inflammatory conditions, and health-promoting antioxidants for use by both food and pharmaceutical industries.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 8