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Artelastocarpin and carpelastofuran, two new flavones, and cytotoxicities of prenyl flavonoids from Artocarpus elasticus against three cancer cell lines
Title
Artelastocarpin and carpelastofuran, two new flavones, and cytotoxicities of prenyl flavonoids from Artocarpus elasticus against three cancer cell lines
Type
Another Publication in an International Scientific Journal
Year
2001
Authors
Cidade, HM
(Author)
FFUP
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Nacimento, MS
(Author)
FFUP
Pinto, MMM
(Author)
FFUP
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Kijjoa, A
(Author)
ICBAS
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Silva, AMS
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Herz, W
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Journal
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Scientific classification
FOS:
Medical and Health sciences > Basic medicine
Other information
Authenticus ID:
P-000-SNC
DOI:
10.1055/s-2001-18845
Abstract (EN):
Further study of one of the fractions from the wood of Artocarpus elasticus furnished two new prenylated flavonoids artelastocarpin and carpelastofuran as well as ethyl 2,4-dihydroxybenzoate. The two flavonoids and the prenylated flavonoids artelastin, artelastochromene, artelasticin, artocarpesin, and cyclocommunin isolated earlier from this species were tested for cytotoxicity in vitro against three human cell lines. All seven flavonoids were active, the cytotoxic effect varying from strong to moderate and with artelastin showing the most potent activity.
Language:
English
Type (Professor's evaluation):
Scientific
No. of pages:
4
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