Targeted metabolites and biological activities of Cydonia oblonga Miller leaves

• Type: Article in International Scientific Journal
• Date: 2012

Authors

Andreia P. Oliveira (Author) FFUP; Rossana M. Costa (Author) Other; Ana S. Magalhães (Author) Other; José A. Pereira (Author) Other; Márcia Carvalho (Author) Other; Paula B. Andrade (Author) FFUP; Branca M. Silva (Author) Other; Patrícia Valentão (Author) FFUP

Journal

Title: Food Research International

ISSN: 0963-9969

Publisher: Elsevier

Indexing

Scopus

Scientific classification

FOS: Medical and Health sciences > Other medical sciences

CORDIS: Health sciences > Pharmacological sciences > Pharmacognosy

Other information

Resumo (PT): Natural products continue to play a significant role in drug discovery and development processes, and many plants have already provided valuable clues for potentially bioactive compounds. Additionally, in recent years it has become evident that significant health risks and benefits are associated with dietary food choice. Nutritional studies recommend the regular consumption of fruits and vegetables, which constitute an essential part of the Mediterranean diet, to favor a healthy life. Several works have showed that quince tree (Cydonia oblonga Miller) is a good and low cost natural source of metabolites with interesting biological properties. Extensive research has been performed on the metabolic profile and biological potential of this species. In particular, quince leaves revealed to constitute a promising natural source of bioactive phytochemicals, suitable for application in nutritional/pharmaceutical fields. In this review phenolics and organic acids composition of quince leaf is overviewed, as well as its antioxidant and antiproliferative properties, in chemical and cellular in vitro systems. Comparisons with green tea, considered by the scientific community as an effective natural antioxidant, were established. <br> <br> Keywords: Cydonia oblonga Miller; Quince leaves; Phenolic compounds; Organic acids; Antioxidant activity; Antiproliferative activity <br> <a target="_blank" href="http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T6V-51962SD-3&_user=2460038&_coverDate=10%2F22%2F2010&_rdoc=1&_fmt=high&_orig=gateway&_origin=gateway&_sort=d&_docanchor=&view=c&_searchStrId=1738769615&_rerunOrigin=google&_acct=C000057398&_version=1&_urlVersion=0&_userid=2460038&md5=25371af4136fba87d6b3ab4bf2841632&searchtype=a "> Texto integral </a> <br> <br>

Abstract (EN): Natural products continue to play a significant role in drug discovery and development processes, and many plants have already provided valuable clues for potentially bioactive compounds. Additionally, in recent years it has become evident that significant health risks and benefits are associated with dietary food choice. Nutritional studies recommend the regular consumption of fruits and vegetables, which constitute an essential part of the Mediterranean diet, to favor a healthy life. Several works have showed that quince tree (Cydonia oblonga Miller) is a good and low cost natural source of metabolites with interesting biological properties. Extensive research has been performed on the metabolic profile and biological potential of this species. In particular, quince leaves revealed to constitute a promising natural source of bioactive phytochemicals, suitable for application in nutritional/pharmaceutical fields. In this review phenolics and organic acids composition of quince leaf is overviewed, as well as its antioxidant and antiproliferative properties, in chemical and cellular in vitro systems. Comparisons with green tea, considered by the scientific community as an effective natural antioxidant, were established. <br> <br> Keywords: Cydonia oblonga Miller; Quince leaves; Phenolic compounds; Organic acids; Antioxidant activity; Antiproliferative activity <br> <a target="_blank" href=" http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T6V-51962SD-3&_user=2460038&_coverDate=10%2F22%2F2010&_rdoc=1&_fmt=high&_orig=gateway&_origin=gateway&_sort=d&_docanchor=&view=c&_searchStrId=1738769615&_rerunOrigin=google&_acct=C000057398&_version=1&_urlVersion=0&_userid=2460038&md5=25371af4136fba87d6b3ab4bf2841632&searchtype=a"> Full text</a> <br> <br>

Language: English

Type (Professor's evaluation): Scientific