The biocompatibility and bioactivity of hemodialysis membranes: their impact in end-stage renal disease

• Type: Another Publication in an International Scientific Journal
• Date: 2019

Authors

Kohlova, M (Author) Other; Amorim, CG (Author) FFUP; Araujo, AN (Author) FFUP; Alice Santos Silva (Author) FFUP; Solich, P (Author) Other; Montenegro, MCBSM (Author) FFUP

Journal

Title: Journal of Artificial Organs

Vol. 22

Pages: 14-28

ISSN: 1434-7229

Publisher: Springer Nature

Indexing

ISI Web of Knowledge - 4 Citations

Scopus - 18 Citations

Other information

Authenticus ID: P-00P-1B4

DOI: 10.1007/s10047-018-1059-9

Abstract (EN): End-stage renal disease is a growing health problem with increasing prevalence and high health care costs. Patients suffering from end-stage renal disease exhibit higher morbidity and mortality rates compared to the general population. These patients, who are treated using hemodialysis, typically suffer from anemia, inflammation, and oxidative stress. Inadequate dialyzer membrane biocompatibility exacerbates these negative side effects. Modifications of the composition of hemodialysis membranes have improved their biocompatibility and improve the patients' quality of life. Recently, the use of dialyzer membranes coated with bioactive compounds has also been proposed to further ameliorate dialysis-associated problems. Based on a survey of the current literature, application of bioactive membranes decreases the inflammation and oxidative stress of patients treated with hemodialysis.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 15