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Molecular Bioinformatics - A Hands-on Course Online

Bioinformatics is a science that integrates concepts of biology, mathematics, statistics and computer science and is dedicated to the study of biological issues through the analysis of molecular data.  Bioinformatics is essential for storing biological data, which grows exponentially, to disseminate information on Web-based platforms, and to analyze and interpret experimental data.  Thus, Bioinformatics is an area of knowledge that is constantly developing and updating.  This course is relevant not only for the training of undergraduate and graduate students but also for the complementary training of health professionals and technicians.

This course combines teaching, for each topic, of the theoretical concepts and bioinformatics tools available, the practical demonstration of these tools and their application by the students in a desktop computer to solve the proposed scientific questions.

Learning methods

The teaching modality of this course will be theoretical-practical classes (TP).  This course combines the exposition, for each topic, of the theoretical concepts and bioinformatics tools available, their practical demonstration and usage by students to solve the proposed scientific questions.  Students will learn by direct contact with bioinformatic programs, with a computer for each student in the classroom.  Given that the tools presented are freely accessible, students will not have any difficulty in solving the proposed exercises using an available computer with wire internet connection.


Course contents

The course is organized in five theoretical-practical sessions held on consecutive days where the following syllabus contents will be taught:

Session 1. Sequence databases: introduction, examples, data retrieval.  Practical exercises I.

Session 2. Sequence comparison: alignment methods, similarity searches, homology, protein motifs and domains.  Practical exercises II.

Session 3. Sequence analysis: prediction of biological properties from DNA, RNA and protein sequences.  Primer design for cloning and gene expression analyses and siRNA design. Restriction maps.  Practical exercises III.

Session 4. Gene ontology: retrieving biological insight from high throughput experiments. Gene expression databases.  Sequence variation and mutations linked to genetic neurological diseases.  Practical exercises IV.

Session 5. Integration of biological data: comparison of gene data sets and multiple databases query.  Practical exercises V.



The evaluation will take into account the individual written works based on solving proposed problems in all sessions (i.e. Practical exercises I to V).
The assessment shall be expressed on a scale of 0 to 20 values.


- Acquisition of theoretical knowledge on bioinformatics tools for the analysis of molecular and experimental data frequently used in the field of life sciences and health;

- Development of bioinformatics practical skills and autonomy (for search, retrieval and analysis of molecular data, analysis and integration of biological data);

- Development of skills to interpret results critically, understanding the advantages and limitations of bioinformatic tools.

Fields of Specialization

Molecular bioinformatics from the user's perspective



Professional Abilities

 - Master essential knowledge of bioinformatics analysis;

- Autonomously use the bioinformatics tools presented, understanding its

- Apply the acquired knowledge on bioinformatics in their professional activity.

- Understand the bioinformatics analyses done by other researchers and promote the establishment of collaborations.


Teaching Language: in Portuguese and partially in English

If there are any foreign participants who do not speak Portuguese, the course will be taught in English.

Teaching mode: e-learning

Number of participants: 
12 (max)/2 (min).

Target audience

Intended for researchers, technicians, graduates, and graduate students (master's and doctoral students) in the Health area (Biological and Medical Sciences).

Specific admission conditions

  • Frequency of higher education or university degree in Biological or Medical Sciences.
  • Basic computer skills are required.

Selection and ranking criteria (in %)

Curriculum analysis (60%):

  - PhD* (5 points)

  - Master/BSc before-Bologna process* (3 points)

  - BSc* (2 points)

  - Postgraduation course/short course (few weeks) (Biological Sciences areas) (1 point)

Professional experience in areas related to the Course (40%):

  - Professional experience (1 point/year; maximum of 5 points)

(*) Criteria are mutually exclusive.

Tiebreaker criterion

Motivation letter.



Course Schedule:

1st edition: 30/01/2023 to 01/02/2023 from 2pm-6pm and 02/02/2023 to 03/02/2023 from 2pm-5pm

2nd edition: 01/05/2023 to 03/05/2023 from 2pm-6pm and 04/05/2023 to 05/05/2023 from 2pm-5pm


Online Applications:

1st edition: 26/09/2022 to 26/10/2022

2nd edition: 09/01/2023 to 08/02/2023

Online Registration:

1st edition: 25/11/2022 to 14/12/2022

2nd edition: 13/03/2023 to 03/04/2023

Tuition fee: 175¤ + 2¤ school insurance (Other institutions)/150¤ + 2¤ school insurance (Faculty of Medicine of University of Porto).
 The fee must be paid upon definitive registration.

Coordinator and Faculty:
Filipe Almeida Monteiro (PhD in Biomedical Sciences), Faculty of Medicine, University of Porto.





Núcleo de Ensino Pós-Graduado
Educação Contínua - Cursos não conferentes de grau
Tel.: +351 220426975
e-mail: posgraduacao@med.up.pt

General information

Teacher Responsible: Filipe Monteiro
Acronym: BioInfOn
Type of course/cycle of study: Continuing Training Unit
Start: 2021/2022
Duration: 18 Hour

Study Plan



  • Molecular Bioinformatics - A Hands-on Course Online (2 ECTS credits)

Predominant Scientific Areas

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