Go to:
Logótipo
Você está em: Start > Courses/CE or Courses/Cycle of Studies or Programmes/Cycle of Studies > MICF > Information for Applicants

MSc in Pharmaceutical Sciences

General information

Official Code: 9494
Acronym: MICF
Description:  

Certificates

  • MSc in Pharmaceutical Sciences (300 ECTS credits)
  • BSc in Basic Studies in Pharmaceutical Sciences (180 ECTS credits)

Courses Units

Anatomy and Histology

MI071206 - ECTS

Anatomy-Histology has as main objective the teaching of the constitution and structure of the human body, organized by systems. Thus, the student should acquire knowledge of concepts and terminology of an anatomical and histological nature about the Human Body. Learning in cell differentiation and in the integration of cells into more complex organizational units such as tissues, organs and systems and their contribution to a given effect will be encouraged. Students should also know how to correlate the knowledge of the structure with the function that the cell/tissue plays in the locomotor, cardiovascular, lymphatic, respiratory, digestive, reproductive, urinary, nervous and endocrine systems, as well as in the sense organs.

In conjunction with the laboratory component, students should be able to identify and locate anatomical parts and characterize the different types of tissues present in organs and systems relating the anatomo-histological characteristics with the function of the system under study. This unit provides students with knowledge bases on the Human Body, essential in the formation of Pharmacists and that are necessary for the study of other units of the MICF such as human physiology, pathophysiology and pharmacotherapy, pharmacology, hematology, toxicology, pharmaceutical care and clinical biochemistry.

Within the scope of transversal skills, this unit aims to contribute to the development and acquisition of skills that are relevant in the exercise of professional activity, namely: i) Cognitive Skills: analytical, critical, reflective and creative thinking; ii) Methodological Skills: time management, problem-solving skills, planning skills and digital skills; iii) Social Skills: interpersonal communication and collaborative work, communication with other health professionals (Doctors, nurses, nutritionists, psychologists, etc.) and with users in the community pharmacy or with citizens in general.

Biophysics and Pharmaceutical Physics

MI231104 - ECTS

The unity of Applied Physics aims to expose students to a set of structured knowledge and concepts of physical and link them with chemical and biological phenomena; provide basic experience in the type of physical measurements leading to quantitative results of interest in Pharmaceutical Sciences. 

Cellular Biology

MI071102 - ECTS

It is intended that the student:

  • Acquires and consolidates knowledge about the basic concepts of Cell Biology/Biochemistry, and the main experimental methodologies for cell studies.
  • Understand the structural characteristics common to all eukaryotic cells: internal and functional organization, expression and transmission of genetic information, structure, and function of proteins.
  • Understand the molecular, structural, and functional complexity of the cell.
  • Achieve the proposed objectives gradually throughout the semester.

In the context of transversal competences, this curricular Unit aims to contribute to the development of the following:

  • Cognitive Skills: analytical, critical, reflective, and creative thinking.
  • Methodological Skills: time management, planning and digital skills.
  • Social Competences: interpersonal communication of scientific information as well as collaborative work.

Pharmacist and Society

MI231103 - ECTS Main learning objectives:
  • Integrate students into the MICF study plan, leading them to know and understand their training objectives in terms of the scientific and technical knowledge to be acquired, the skills and attitudes to be developed, as well as the principles of ethics and social awareness that characterise the profession of Pharmacist. Implement a methodology for the elaboration of a digital portfolio, in the context of the objectives of the MICF;
  • Contextualise the syllabus and objectives of the MICF in the knowledge, skills and attitudes of pharmacists defined in the European Directive, in the ‘Acts of the Pharmacist Profession’ of the ‘Order of Pharmacists’ and in documents from international bodies, namely the ‘International Pharmaceutical Federation’ (FIP);
  • Relate the Master in Pharmaceutical Sciences to the Profession of Pharmacist, contributing to the formation of the professional and scientific identity of the future pharmacist;
  • Identify the current pharmaceutical activities in the different fields of professional and scientific practice, contextualising them in the historical evolution of the profession and in a probable future development of it;
  • Substantiate the basic concepts related to the medicine, in the context of its historical framework, as well as the main pharmaceutical forms and routes of administration.
  • Promote reflection on Deontology, with a special focus on pharmaceutical practice.
  • Implement a digital portfolio development methodology in the context of the MICF's objectives

Within the scope of transversal competences, this Curricular Unit aims to contribute to the development of the following competences:
  • Cognitive: reflective and creative thinking;
  • Methodological: planning capacity and digital skills;
  • Social: interpersonal communication and collaborative work.

Applied Mathematics and Biostatistics

MI231101 - ECTS

The learning objectives are intended for the student to acquire knowledge in:

  1. Basic use of the Microsoft EXCEL software tool;
  2. Basic concepts for solving problems that involve the organization of data in tabular form, using matrix operations
  3. Basic probability theory, necessary for the exposition of the subject on statistical inference;
  4. Descriptive statistics;
  5. Random variables and probability distributions
  6. Univariate discrete and continuous distributions, with  application in the fields of health science;
  7. Various statistical inference techniques; in particular, the student should understand the underlying mathematical model and the assumptions that this model presupposes;
  8. Choice and application of statistical techniques to concrete problems in the area of Natural Sciences and Health;
  9. Basic calculation concepts to concrete situations in the area of Health Sciences - exponential function and logarithmic function, rates of variation and derivation, function graphs and integration.

Additionally, it is intended for the student to develop transversal skills such as critical thinking, ability to interpret and communicate the results obtained by statistical analysis.

General and Inorganic Chemistry

MI071105 - ECTS

The objectives defined for the General and Inorganic Chemistry curricular unit are naturally related to its elementary, generalist and pedagogical support role, but its approach and development will be a consequence of the specific level of knowledge displayed by the students, and of its subsequent evolution . On the other hand, and taking into account the importance that the General and Inorganic Chemistry unit may have in order to obtain solid and interdisciplinary training in the area of ​​Pharmaceutical Sciences, its program and the subjects under study will take into consideration to provide students with chemistry knowledge related, as far as possible, to the exercise of pharmaceutical activity.

Thus, the mais objectives are the following:


a) Revision, uniformity and consolidation of basic and essential chemical knowledge.

b) Systematisation of concepts and development of identification, interpretation and resolution skills regarding problems and situations related to chemical phenomena or reactions.

c) Acquisition of advanced knowledge in distinct chemical areas, whenever possible with a pharmaceutical perspective.

d) Motivation of students to the need of a complementary auto-didactic formation involving the consolidation of the principles, ideas and concepts acquired in classes, by means of bibliographic material, data bases, and other information available in the Internet, etc.

Biochemistry

MI231209 - ECTS

The aim is for students to acquire good knowledge of fundamental structures and biochemical processes that will help them understand, for example, the pathology associated with certain dysfunctions and sustain them to better understand the contents of other disciplines such as microbiology, hematology, immunology, physiology, Pharmacology and Toxicology.

Bibliography advised:

Devlin, Biochemistry With Clinical Correlations, 8ª ed., 2019; Halpern, Bioquímica. Organização Molecular da Vida, 2008 (Lidel); Lehninger, Principles of Biochemistry, 8ª ed., 2021; McKee, Biochemistry, The Molecular Basis of Life, 5ª ed., 2011; Stryer, Biochemistry, 9ª ed., 2019

 

Human Physiology

MI231206 - ECTS

Analyse and interpret the functioning of the human body, in a perspective of interaction between cells, organs and systems that result from a process of evolution by natural selection.

Discuss scientifically the mechanisms that operate and coordinate vital functions, establishing connections with previous knowledge of biology, biochemistry, anatomy, and histology.

Promote the knowledge of the normal function of the human body, introducing essential concepts for the future understanding of pathophysiological changes and of therapeutic strategies.

Apply the scientific method in laboratorial classes, promoting the planning, performance and analysis of physiological experiments, as well as the interpretation, discussion and communication of results.

Promote the development of team work skills, in a balanced manner with the development of autonomous thinking, decision, and performing skills.

Analytical Chemistry

MI071208 - ECTS

Analytical Chemistry as a core curricular unit of the Integrated Master in Pharmaceutical Sciences aims to contribute in a solid and integrated way to training in the area of ​​the chemistry of the future pharmacist and master in pharmaceutical Sciences. It aims to provide concepts and skills that allow understanding and explaining the principles of analytical chemistry, its interconnection with concepts taught in other curricular units of the integrated Master and its importance in the scope of quality control in Pharmaceutical Sciences.

As well as learning objectives:

General: Interconnection of the chemical concepts of acid-base, oxidation-reduction, complexation and solubility with some biological phenomena and their role in the development of drugs. Theoretical and practical training required to understand and resolve the analytical methodology applied in the control of real samples, of biological, pharmaceutical, environmental or food origin. Ability to select the appropriate procedures for the design, application and evaluation of reagents, solutions, and analytical methods. Estimate the risks associated with the use of chemicals and laboratory processes Estimate the reliability of analytical results Specifics: Knowledge of chemical balances (acid-base, oxidation-reduction and complexation, solubility) in solution. Application of this knowledge for the quantitative analysis of substances of biological and chemical origin. Importance of quality assurance and validation of methods in terms of drug production and laboratory control in different areas

 

Organic Chemistry I

MI071101 - ECTS

Classify the reactions of organic compounds, and characterize the structural aspects that confer and influence their reactivity and their physicochemical properties.
Understand the chemical reactions and mechanically justify the facts that have occurred.
Apply the knowledge of the reactivity of the different functional groups in order to obtain new compounds, that is, to project the knowledge acquired in organic synthesis, namely in the synthesis of potential drugs.
Acquire the concept of molecule geometry in the space associated with the study of stereochemistry.
Stimulate and develop the capacities for reflection and criticism, by carrying out review and application exercises of the acquired knowledge.
Develop scientific skills and attitudes, namely deductive reasoning, rigor, teamwork and observation.
Plan laboratory experiments, organize and interpret experimental data.
Apply laboratory safety rules and good practices in the use of material and equipment.
Develop the capacity for experimental, critical and self-assessment of the experiences made. Prepare accurate and reproducible reports.

Physical-Chemistry

MI071207 - ECTS

The aim of this curricular unit is the study of three large areas of physical-chemistry: thermodynamics, kinetics and heterogeneous systems. This therefore consists of the study of chemical thermodynamics – presentation of thermodynamic concepts, their chemical application and the study of biochemical thermodynamics – their application in the thermodynamic knowledge and interpretation of biological and microbiological phenomena, their application in the areas of life sciences and biotechnology. In relation to kinetics, this includes not only the study of chemical kinetics and catalysis but also enzymatic kinetics and enzymatic inhibition. Concerning heterogeneous systems, micelle and liposome systems will be studied, with special emphasis on those applicable as drug delivery systems or for the study of distribution, bioavailability and mechanism of action/interaction with biomembranes of drugs.

Metabolism Biochemistry

MI232110 - ECTS

It is intended that students acquire knowledge about:

  • the metabolic pathways of the main biological molecules (carbohydrates, lipids, amino acids and nucleotides);
  • the mechanisms of metabolic regulation;
  • the interrelationship between different metabolic pathways;
  • metabolic adaptations during the fasting-fed cycle and after physical exercise;;
  • metabolic changes associated with some pathologies.

Acquisition of the experimental methodology necessary for the characterization and evaluation of biochemical functions performed by sub-cellular structures (mitochondria).

Development of good practices for the use of all laboratory equipment.

Molecular Genetics

MI072111 - ECTS

Study of the basic mechanisms that allow the genetic DNA transmission based in replication, transcription, processing and translation processes. Modifications at DNA level analysis after recombination, mutation, transposition, transduction and viruses. Study of DNA repair mechanisms. Prokariotic and eukariotic gene expression regulation analysis to understand how gene expression is controlled and cells synthesize the right proteins at the right time in the right amounts. Study of the molecular mechanisms associated with cancer and related processes that involve the cell cycle regulation, mutations in proto-oncogenes and anti-oncogenes. The use of DNA replication technology as a dominant approach for studying the basic biological processes that allow cloning and identification of genes, analysis of genetic expression and regulation, diseases diagnosis, production of drugs and vaccines, and gene therapy.

Instrumental Methods of Analysis

MI232112 - ECTS

The natural, semi-synthetic and synthetic chemical / biological substances, as well as the instrumental devices that have potential benefit in protecting and promoting human health, constitute the axiom of specialization and pharmaceutical activity. The pharmaceutic profession is hence committed with the discover, evaluation of the effects, production, proposal and dissemination, dispensing and regulation of these substances use in a safe and effective manner. In accordance to such profile, this curricular unit intends to provide the trainee with basic knowledge and skills in common laboratory instrumentation use when the quality of chemical / biological substances and the respective effects is intended, whatever its context of the analysis: research, scale production with quality criteria, simple laboratory follow-up of its application in clinical trials, or in the service of public health. More broadly, this course aims to prepare pharmaceutical professionals with critical look over experimental and scientific information.

To achieve this end, two complementary objectives are established:

- Train the student for rational use of instrumental techniques and methods based on the interaction of light with matter, aiming biological and chemical characterization and quantification.

- Train the student in the use of statistical / computer tools which, according to the ICH Q2 and EURACHEM / CITAC guidelines, certify and measure the quality of the instrumental methodology and, therefore, the significance of the information made possible by it.

General Microbiology

MI072217 - ECTS

This is the first discipline in the area of Microbiology, of this course. The main goal of this unit is to make students sensitive to the Microbiology relevance to Life Sciences with particular emphasis in Bacteriology.
Theoretical program aims to drive students in the study of Microbiology basics showing general characteristics of microbial entities relating with hosts and the environment. Bacterial cell organization, ultra-structure and metabolism of bacterial cell will be studied as a model of the most relevant agents of infection and microbial contamination. Bacterial genetics and antimicrobial therapeutics will be addressed in an integrated way.
Laboratorial program aims to introduce students in classical methodologies in Microbiology as morphological characterization, metabolism, genetics and antimicrobial susceptibility and also support experimentally concepts discussed in theoretical classes.

Organic Chemistry II

MI071209 - ECTS

Study of the basic principles of Organic Chemistry relevant to the Pharmaceutical Sciences student and the pharmaceutical professional. Development of critical thinking and spirit using examples and exercises that involve simpler molecules and evolve to pharmaceutical and biochemical molecules. Understanding and predicting the behavior of carbon compounds using the representation of reaction mechanisms. Study of the main organic families. Acquisition of basic experimental methodology used in clarifying structure, either by chemical or spectrometric means. Evolution of student competence in the laboratory, developing good practices in the use of material and equipment while at the same time acquiring a greater awareness of laboratory safety rules. b) A basic knowledge of Organic Chemistry from the Organic Chemistry I subject is assumed. The presence and constant revision of this knowledge during the Organic Chemistry II subject is recommended.

Bromatology and Bromatological Analysis

MI232216 - ECTS

1 - The concept of Bromatology and Bromatological analyses. Connection with food regulation and standardization of analytical methods.
2 - Knowledge about foodstuffs composition concerning major and minor components, including desirable and undesirable compounds.
3 - Preparation of samples, execution and interpretation of bromatological analyzes to obtain information on the composition of foods and their biochemical transformation during production, maturation and storage, as well as ensuring the authenticity of foods. 
4 - Most significant questions of the modern world related to feeding and food safety. 

Pharmacology I

MI073229 - ECTS

LEARNING OUTCOMES
On completion of this course, the student should understand the general principles of Pharmacology, namely the general mechanisms of drug/receptor interaction and the qualitative and quantitative ways of characterising the action of drugs. The student should also know the general principles of pharmacokinetics, understanding how the body, through metabolising mechanisms or barriers, conditions the ADME (Absorption, Distribution, Metabolisation and Excretion) of drugs. They are also expected to be able to understand the main factors that influence a population's response to a drug and interpret them in the light of the general principles of pharmacodynamics and pharmacokinetics.
Within the scope of Special Pharmacology of organs and systems, the student is expected to identify the main sites of pharmacological intervention in neuropsychopharmacology, know the main groups of drugs and the pharmacological bases for their use in pharmacotherapy based on specific pathophysiology.


Immunology

MI072113 - ECTS

Main learning objectives:
The aim is for students to develop the ability to:

  • Understand the basic concepts regarding the components that constitute the tissues and organs involved in the immune response.
  • Gain knowledge of the composition of the various cellular and molecular constituents present in the biological fluids associated with the immune response.
  • Acquire skills in basic experimental methodologies used to determine immunological parameters, with emphasis on vaccine-induced protection mechanisms and allergic reactions to drugs.
  • Recognize the importance of immunotherapy in the context of health.

Transversal skills:
This course aims to contribute to the development of the following skills:

  • Cognitive skills: analytical, critical, reflective, and creative thinking.
  • Methodological skills: time management, planning ability, and digital competencies.
  • Social skills: interpersonal communication and collaborative work.

Throughout the semester, students are expected to demonstrate progress in experimental practice, achieving greater autonomy and the ability to apply their knowledge to new situations.

Intrumental Methods of Analysis II

MI072218 - ECTS

Pharmaceutical Chemistry I

MI072220 - ECTS

In this UC it is intended that students acquire the general principles in pharmaceutical and medicinal chemistry and contact the sources, methodologies and strategies used to obtain new drugs and thus be able to propose molecular changes, interpret the structure-activity relationship (SAR) , metabolism and mechanisms of action at the molecular level for different groups of drugs.

With this objective it is intended that students:

* use appropriate terminology to explain basic chemical, pharmacological and therapeutic concepts;

* acquire, understand, apply and analyze information on the chemical structure of drugs and the relationship with therapeutic applications, as a tool for the discovery of new drugs;

* select a suitable drug candidate based on knowledge of the chemical, physical properties of a molecule;

* apply the knowledge of structural characteristics to predict mechanisms, adverse effects, metabolism, solubility, acid / base characteristics, potential drug interactions and therapeutic effects of potential drugs.

* have a perception of computational methods

* understand the management of intellectual property

* understand Pharmaceutical Analysis in the discovery, development and production of drugs; in the drug quality and monitoring.

They must acquire an overview of the drug development process from an industrial point of view and on clinical trials and safety.
More particularly, at the level of the therapeutic classes covered, students will be able to:

* acquire an overview of the pharmaceutical and medicinal chemistry of chemotherapic drugs.

* identify the chemical and / or pharmacological classification to which a drug belongs based on the pharmacophore;

* predict therapeutic applications for individual drugs based on knowledge of the chemical and / or pharmacological classification and based on the structure-activity relationship (SAR) and the structural characteristics responsible for the interaction with biological targets;

* select within a chemical and / or pharmacological class a lead compound based on structural characteristics that affect absorption, distribution, metabolism and excretion;

At the level of case studies of bioactive compounds in research, students should be able, in the context of research, to know how to apply the acquired knowledge and their ability to understand, as well as to solve problems, in new and unfamiliar situations, broad and multidisciplinary contexts.




- The therapeutical applications shall be related to "Acto Farmacêutico".

With classes on application of concepts, students will have the opportunity to integrate knowledge, deal with complex or multidisciplinary issues, develop solutions and be able to communicate their conclusions and the knowledge and reasoning underlying them, whether to specialists or non-specialists, in a clear and unambiguous way.


- In the laboratory component, students are expected to acquire skills in common techniques used in pharmaceutical and medicinal chemistry laboratories and related to the topics covered in theoretical classes. Furthermore, it is intended that students acquire an experimental basis for interpreting theoretical concepts, namely molecular recognition and factors that influence the activity of drugs (pH, log P, solubility); as well as acquire knowledge about methodologies used in the isolation and synthesis of drugs, taking into account programmatic coordination with the subject matter of theoretical classes.

Pharmaceutical Technology I

MI072219 - ECTS To provide students with the knowledge of the terminology and concepts used in Pharmaceutical Technology as well as technical and scientific knowledge underlying medicines, in particular those relating to pharmaceutical solid dosage forms – powders, granules, tablets, coated tablets and capsules –, in order to provide them the necessary scientific bases and professional skills, namely in the formulation, preparation, quality control, storage, preservation and dispensing of these medicines.

Food and Health

MI233122 - ECTS

The chosen themes and the way to present them in the classes aim to:

  1. a) inform students about the importance of Food (diet) in the general state of the individual, health and well-being; motivate them to implement this care and disseminate this knowledge to close people and even use this information at a professional level, whenever it suits. The main objective is to increase the level of knowledge in the area, presenting examples to facilitate the acquisition of knowledge.
  2. b) prepare students, as health technicians, for the performance of the profession in the Community;
  3. c) encourage students to develop the information obtained from different sources, transmitting it in a clear, simple and enlightening way to the Community; and
  4. d) provide students with knowledge of food and nutrition that allows them to include in the pharmaceutical advice, diet and diet therapy, so relevant in some pathologies.

The problems of environmental sustainability and the influence on the health of living beings and the quality of available food will also be addressed. The problems of food availability, One Health, climate change and circular economy will also be addressed, always with the concern for the health of populations

Whenever possible, experts in the different areas of study of the UC will be invited, namely professionals from the Community Pharmacy, the Hospital Pharmacy and the legislative area. In this way, students have contact with the different areas of work related to UC, acquiring more skills for future professional choices.

Pharmacology II

MI074132 - ECTS

The course unit (CU) of Pharmacology II is integrated within in a sequence of CUs, namely with Pharmacology I and a Pathophysiology and Pharmacotherapy I and II. Taken together, these CUs are intended to help the student to:

  1. Understand the mode of action of drugs in humans;
  2. Understand the factors that influence the permanence of drugs in the body and the methods that can be used to calculate and adjust doses and the dosage regimen that ensure the maintenance of appropriate concentrations to achieve the desired therapeutic effects;
  3. Understand the occurrence of adverse reactions and explain those arising from predictable pharmacodynamic responses;
  4. Understand interindividual variability in drug response as a function of genetic and non-genetic factors;
  5. Know the most widely explored pharmacological targets for therapeutic purposes, the most representative drugs in each group and the contexts in which they are clinically used;
  6. Understand the general aspects of the pathologies that are the main indications for each group of drugs.

In this context, the CU of Pharmacology II hasa global aim to capacitate the students with the necessary scientific knwledge, professional attitudes and technicl skills in order to develop, as independent professionals, activities that are part of the Pharmaceutical Act, namely the interpretation and evaliation of medical prescriptions; information on human medicines and communication among health preofessional and patientes/caregivers to promote the rational use of medicines; follow up the use of human medicines and medical devices.

As specific objectives, the CU of Pharmacology II aims to enable the student with consistent and critical pharmacological and pharmacotherapeutic knowledge, attitudes and technical skills in the areas of cardiovascular and endocrine pharmacology. Thus, in each chapter, key points will be selected in order to:

  1. Explain the different pathophysiological mechanisms of the diseases and the therapeutic aims of the various pharmacological and non-pharmacological interventions;
  2. Instruct the reference drugs of each therapeutic class;
  3. Instruct the historical development of reference drugs and the pharmacodynamic and pharmacokinetic limitations that have conditioned and / or will condition the appearance of new drugs from each group;
  4. To elucidate the basic pharmacodynamic activity resulting from acting on each target;
  5. Instruct the main pharmacological effects resulting from this activity;
  6. Instruct the present therapeutic indications and future perspectives of new drugs, or new indications.

Within the scope of transversal competences, this UC aims to contribute to the development of:

  • Cognitive skills: analytical, critical, reflective and creative thinking;
  • Methodological competences: careful selection of relevant information, time management and planning capacity;
  • Social skills: interpersonal communication (oral and written) and collaborative work.

Phytochemistry and Pharmacognosy I

MI072216 - ECTS

Knowledge of metabolic pathways of plant biosynthesis (particularly acetate and shikimate pathway,);
Knowledge of chemical groups and biosynthetic pathways of origin of specialized metabolites;
Knowledge of drugs of natural origin, either included or not in pharmacopoeias:
-with pharmacological actions and used in therapeutics
-containing starting materials for the semisynthesis of pharmacologically active molecules by the pharmaceutical industry
- relevant for pharmaceutical and food industries.

Pharmaceutical Chemistry II

MI073121 - ECTS
As for Pharmaceutical Chemistry I, in this CU it is intended that:

-for various classes of drugs, students are able to interpret and predict the structure-activity relationships, metabolism, as well as interpret the molecular mechanism of action of the drugs classes.

-therapeutic applications are related to activities under the Pharmaceutical Act.

-acquired knowledge of the methodologies used in the synthesis and analysis of drugs in laboratorial classes which are in programmatic coordination with the theoretical lectures. 
 
With this objective it is intended that students:

* use appropriate terminology to explain basic chemical, pharmacological and therapeutic concepts;

* acquire, understand, apply and analyze information on the chemical structure of drugs and the relationship with therapeutic applications, as a tool for the discovery of new drugs;

* select a suitable drug candidate based on knowledge of the chemical, physical properties of a molecule;

* apply the knowledge of structural characteristics to predict mechanisms, adverse effects, metabolism, solubility, acid / base characteristics, potential drug interactions and therapeutic effects of potential drugs.

More particularly, at the level of the therapeutic classes covered, students will be able to:

* acquire an overview of the pharmaceutical and medicinal chemistry of chemotherapic drugs.

* identify the chemical and / or pharmacological classification to which a drug belongs based on the pharmacophore;

* predict therapeutic applications for individual drugs based on knowledge of the chemical and / or pharmacological classification and based on the structure-activity relationship (SAR) and the structural characteristics responsible for the interaction with biological targets;

* select within a chemical and / or pharmacological class a lead compound based on structural characteristics that affect absorption, distribution, metabolism and excretion;

At the level of case studies of bioactive compounds in research, students should be able, in the context of research, to know how to apply the acquired knowledge and their ability to understand, as well as to solve problems, in new and unfamiliar situations, broad and multidisciplinary contexts.

With classes on application of concepts and the panel communication, students will have the opportunity to integrate knowledge, deal with complex or multidisciplinary issues, develop solutions and be able to communicate their conclusions and the knowledge and reasoning underlying them, whether to specialists or non-specialists, in a clear and unambiguous way.

In the laboratorial classes it is intended that the student acquire knowledge on methodologies used on the synthesis and analysis of drugs, having in line a programmatic coordination with the theory lectured.

Pharmaceutical Technology II

MI073124 - ECTS

This Course aims to give students the capacity to prepare commonly prepared formulations, allowing them to assume responsabilities at industrial level, in what concerns solutions, emulsions, coloidal dispersions and suspensions.

Bacteriology

MI073122 - ECTS

The contribution of human bacterial microbiota to health and disease. Evaluation of the effectiveness of preventive and corrective measures of diseases associated with the alteration of the bacterial microbiota.

Bacterial diversification: implications for identification, adaptation to antimicrobial agents and pathogenicity.

Methodologies for the study of communities and bacterial strains (classical to “omics” methodologies): resolution capacity, applicability and limitations.

To evaluate, predict and communicate the transmission routes, the risk of infection, commonly used diagnostic procedures and control measures (prophylactic and therapeutic) of bacterial species of greatest clinical relevance to humans.

Within the scope of transversal competences, this Curricular Unit aims to contribute to the development of the following:

Cognitive skills: analytical, critical, reflective and creative thinking;

Methodological skills: resource management, ability to perform specific laboratorial and data analysis methodologies, and digital capacity;

Social Skills: interpersonal communication and collaborative work

Biopharmacy and Pharmacokinetic

MI074256 - ECTS

Pharmacist and Society

MI243246 - ECTS

The students should aquire an integrated vision of the History of Pharmaceutical Sciences, developping competences that help him to understand the knowledges learned during the obtention of the master degree  according to the evolution of mankind, specially in what concerns the causes and the treatemnt of diseases.

Pathophysiology and Pharmacotherapy I

MI074236 - ECTS Pathophysiology and Pharmacotherapy I is a curricular unit (CU) integrated into a sequence of CUs that include Pharmacology I and II and Pathophysiology and Pharmacotherapy II. This sequence of CUs aims to be a core component of the General Objective of the Integrated Master in Pharmaceutical Sciences at the FFUP, once they provide the student with deep knowledge about the relationship drug/patient.Taken together, these CUs have the overall goal of helping the student to:
1. Understand the way drugs act in man;
2. Understand the factors that determine the permanence of the drugs in the body and know the methods that allow to calculate the doses and adjust the dosage regimens to ensure the maintenance of the adequate concentrations to obtain the desired therapeutic effects;
3. Understand the occurrence of adverse reactions and explain those arising from predictable pharmacodynamic responses;
4. Understand interindividual variability in response to drugs in functions of genetic and non-genetic factors.
5. To know the pharmacological targets most exploited for therapeutic purposes, the most representative drugs of each group and the contexts in which they are used clinically.
6. Understand the general aspects of the pathologies that are the main indications of each group of drugs.
7. Identify relevant information on new drugs, their mechanisms of action and pharmacological targets where they operate.

When considering the FIP Global Competency Framework v2, Pathophysiology and Pharmacotherapy I contributes to virtually all the competencies included in the Pharmaceutical Care competency cluster, namely 2.1 Assessment of medicines, 2.2 Dispensing, 2.4 Medicines, 2.5 Monitor medicines therapy, 2.6 Patient consultation and diagnosis, as well as competencies from other clusters like 1.3 Medicines information and advice, and enables students to a more effective Interprofessional collaboration and increases their Communication skills.



Lectures will be used for generic presentations of each of the themes, aiming to give the students an overview of each chapter that prepares them for autonomous learning and for a continuous education throughout their professional life.

In each chapter, key points will be selected to help the student:

1. To understand the pharmacodynamic fundamentals resulting from the performance in each target;
2. To know the main pharmacological effects resulting from this action, regardless of whether they are exploited for therapeutic purposes or can be classified as adverse reactions to the present therapeutic indications;
3. Know the historical context of your discovery
4. Understand the disease and the therapeutic objectives of the various pharmacological interventions.
5. To know the reference drugs of each class and the pharmacodynamic and pharmacokinetic limitations that conditioned and/or condition the appearance of new drugs in the group;
6. To know the present therapeutic indications and future perspectives of new drugs or new indications.

In this context, the curricular unit of Pathophysiology and Pharmacotherapy I has as specific objectives:
1. To help the student to obtain a pharmacological and pharmacotherapeutic knowledge consistent and critical, suitable for graduation in Pharmaceutical Sciences in the area of immunopharmacology;
2. To know the main groups of drugs used in the areas addressed, their mechanisms of action and adverse reactions as well as particularities about their clinical use.

Phytochemistry and Pharmacognosy II

MI073125 - ECTS

Knowledge of the metabolic routes of plant biosynthesis and secondary metabolites.

Use of plants in therapeutics as source of:

  • bioactive molecules directly used by pharmaceutical industry (especially alkaloids and cardiotonics)
  • molecules to be used as basis in semi-synthesis of other compounds for therapeutic application
  • leading structures for the study of new molecules with therapeutic interest (mainly steroids and alkaloids).

Mycology

MI073226 - ECTS

Understanding the importance of fungi in our surrounding environment and their importance as agents of animal infection.
Acquisition of knowledge necessary for the manipulation of fungi in the laboratory and the principal characteristics for their laboratorial identification.
Understanding the pathogenicity of fungal infection and the means available for its prevention and treatment.
The importance of fungi in biotechnology/industry.

Within the scope of Transversal Competencies, this UC aims to contribute to the acquisition of the following competencies:
Cognitive; Critical thinking and integration of concepts learned in different UC,
Methodological methods; Time and resource management, stimulate the ability to plan tasks,
Social Services; Promote inter-personal communication in person.

Pharmaceutical Technology III

MI073228 - ECTS

Aims:
To integrate and apply by the students’, knowledge acquired in Course Units propaedeutic and in the two Pharmaceutical Technologies previously taught.
Acquire knowledge that enables them to formulate, prepare and ensure the quality of skin preparations, rectal, vaginal and oromucosal.
To know the process of industrial production for the group of the semisolids preparations for skin application and preparations for applying in vaginal, rectal and oromucosal mucous membranes.
To know the process for the production of transdermal patchs and the varieties of forms existing on the market.

To achieve these goals, the student must apply 162 h (6 ECTS x 27 h), of which 26 h correspond to lectures and 22 h to laboratory classes. Of the remaining 114 h, circa 4 h will correspond to the evaluation and the remaining 110 h will correspond to work/study time.

Biotechnology and Advanced Pharmaceutical Technology

MI234131 - ECTS To apply the knowledges that the student aquired during propedeutic lectures and in Tecnologia Farmacêutica I, Tecnologia Farmacêutica II and Tecnologia Farmacêutica III.

Know the concept of Biotechnology: definition and main stages in the development of Biotechnology. Distinguish the different areas of application of Biotechnology and learn about biotechnological processes. Give special emphasis to Pharmaceutical Biotechnology. Know the regulatory and bioethical aspects applied to Pharmaceutical Biotechnology.
Acquire knowledge that will allow them to formulate, prepare and guarantee the quality of ophthalmic, nasal, parenteral and new drug delivery systems for modified release for the administration of biopharmaceuticals and conventional drugs.

The student must study for 122 hours (4.5 ECTS x 27 hours), from which 26 correspond to theoretical lectures and 20 to laboratorial practices. From the other 76 hours, 4 correspond to evaluation and the other 72 to study hours.

Pharmaceutical Sciences

MI203297 - ECTS

This UC should contribute to the acquisition of knowledge and promote the development of attitudes and competences in the scientific areas Health Sciences / Physical Sciences / Natural Sciences / Technological Sciences / Social Sciences established under the terms of the optional UCs present in Table No. 1 of Order 7536/2023 (concerning the Curricular Structure of the integrated study cycle leading to a Master's degree in Pharmaceutical Sciences).

The specific objectives of this curricular unit (UC) correspond to the objectives of the university teaching UC that is credited by the Scientific Commission (ComC) of the Integrated Master in Pharmaceutical Sciences (MICF), or by commissions to which the ComC delegates competences for this. The accreditation of the training is dependent on the level of contribution of their learning outcomes to the objectives of the MICF.

Dermopharmacy and Cosmetics

MI074266 - ECTS 1. To provide students with technical and scientific knowledge underlying the human skin, the most frequent dermatoses in Portugal and the medicines suitable for each situation, including their personalized preparation as compounded medicines, in order to give them scientific bases and professional skills for preparing dermatological medicines and cosmetic products, either at the Community or Hospital Pharmacy, and for counseling dermatological medicines (industrialized and compounded).

2. To provide students with technical, scientific and regulatory knowledge underlying cosmetic products, in order to give them the necessary scientific bases and professional skills to intervene professionally in the entire cosmetics value chain, namely in research and development, manufacture, distribution, regulatory affairs, cosmetovigilance, training and counseling.

Entrepreneurship, Innovation and Intellectual Property

MI244171 - ECTS Learning Objectives: The aim is for students to develop technical skills in the area of intellectual property, as well as the ability to assess the potential and feasibility of a business idea in the healthcare/pharmaceutical field. Additionally, students are to achieve an understanding of: - Business plans and models - Customer segments and competition - Intellectual property in the pharmaceutical context (copyright and industrial property) - Innovation cycle/management

Veterinary Drugs

MI204194 - ECTS
With a focus on the intervention of the pharmacist in animal health care, it is intended that the students know the drugs for veterinary use from a pharmaceutical chemistry perspective and considering the most relevant therapeutic aspects.

The discovery, planning and development of drugs for veterinary use will be treated, seeking to establish the parallelism and difference with drugs for human use. Aspects of Pharmaceutical Chemistry involving the drugs used in animals will be addressed, namely, the establishment of the structure-activity relationship, metabolism and mechanisms of action at the molecular level for different groups of drugs. The impact on public health and the environment of veterinary drugs and their residues will be discussed. Examples of the integration and application of this knowledge in pharmaceutical dispensing and advice will be given.

Pathophysiology and Pharmacotherapy II

MI075139 - ECTS The Physiopathology and Pharmacotherapy II is part of a sequence of UCs that include Pharmacology I and II and Physiopathology and Pharmacotherapy I.

As a whole, these UCs have the general objective of learning helping the student to:

  1. Understand the way in which drugs work in humans.
  2. Understand the factors that condition the permanence of drugs in the body and to know the methods that allow to calculate the doses and adjust the dosage regimens to guarantee the maintenance of the appropriate concentrations to obtain the desired therapeutic effects.
  3. Understand the occurrence of adverse reactions and explain those resulting from predictable pharmacodynamic responses.
  4. Understand the inter-individual variability in response to drugs in function of genetic and non-genetic factors.
  5. To know the most explored pharmacological targets for therapeutic purposes, the most representative drugs in each group and the contexts in which they are used clinically.
  6. Understand the general aspects of the pathologies that are the main indications of each group of drugs.



Theoretical teaching will be used for generic presentations of each of the themes, seeking to give students a global view of each chapter that prepares them for autonomous learning and for continuous updating throughout their professional life. Thus, in each chapter, the key points that help the student to:

1. Understand the pharmacodynamic fundamentals resulting from the performance in each target;

2. Know the main pharmacological effects resulting from this action, regardless of whether they are explored for therapeutic purposes or may be classified as adverse reactions to the current therapeutic indications;

3. Understand the disease and the therapeutic objectives of the various pharmacological interventions;

4. To know the reference drugs of each class and the pharmacodynamic and pharmacokinetic limitations that have conditioned and/or will condition the appearance of new drugs in the group;

5. To know the current therapeutic indications and future perspectives of new drugs or new indications.


In this context, the curricular unit of Pathophysiology and Pharmacotherapy II has as specific objectives, to assist the student to obtain a pathophysiological and pharmacotherapeutic knowledge, consistent and critical, suitable for graduation in Pharmaceutical Sciences in the areas of cancer and infection; special protocols used in the treatment of chronic infectious diseases and associated symptoms; to know the main groups of drugs used in the areas covered, their mechanisms of action and adverse reactions, as well as particularities about their clinical use.

Haematology

MI074133 - ECTS

 

The aim of the teoric component of these studies is to prepare the students with a solid basis in hematology, giving a particular emphasis in the most prevalent hematologic disorders in Portugal. The laboratorial component, strongly linked to the teoric component, prepares the student to  perform the hematological studies needed to the first aproach to an hematological patient and to its correct reading and interpretation. It is important for a pharmacist the knowledge of the medicines used in hematological disorders and the laboratorial assays used for their diagnosis and monitoring.

 

Instrumentation, Techniques and Methods in the Clinical Laboratory

MI074178 - ECTS To provide the students with an integrated overview of the basic principles of operation of laboratory equipment, instrumental techniques and analytical methodologies most commonly used in Clinical Laboratories (including the "Bioanalytical" area).
The ultimate goal is the students become superiorly skilled on the more technical/technological aspects of the entire laboratory activity, particularly in terms of proper and efficient use of laboratory equipment, with deep knowledge of their basic principles of operation, and the development, implementation, validation and control of analytical procedures/ methodologies.
This curricular unit should be regarded as "nuclear" for those students intending a future laboratory activity as analysts in the biomedical field.
As transversal competences, this curricular unit aims to contribute to the development of the following: a) cognitive: analytical, critical, reflective and creative thinking; b) methodological: time management, problem-solving, learning strategies and digital skills; c) social: interpersonal communication and teamwork.

Introduction to Pharmaceutical Marketing

MI244168 - ECTS

Food Microbiology

MI073279 - ECTS

Students should understand:
The current impact of food-borne diseases on public health, the main microbiological hazards and contamination routes of  water, food and surfaces, the risk behaviors associated with food handling, preventive measures for the transmission of pathogens to humans and the current methodologies used in the microbiological analysis of water, food and surfaces.

Within the scope of transversal skills, this Curricular Unit aims to contribute to the development of the following skills: 
-Cognitive: analytical, critical, reflective and creative thinking;
-Methodological: planning ability, ability to execute various laboratory and data analysis methodologies and digital skills;
-Social: interpersonal communication and collaborative work.

Parasitology

MI074130 - ECTS

The discipline of Parasitology, has the general objective of providing the fundamentals of the association between living beings with particular emphasis on parasitism that compromises the health of man and some animals. Parasitic infections are of significant importance in the world around us, from the richest world in the northern hemisphere to the poorest parts of Africa and require special vigilance as a result of the climate changes we are witnessing daily. The dicipline of parasitology aims to raise students' awareness of this reality.

Drug Design and Sustainable Synthesis of Drugs

MI224181 - ECTS

The general objective of this curricular unit is for the student to get in touch with the various strategies/methodologies for planning and sustainably obtaining drugs through a Project-based learning model. The Student, having acquired a set of essential knowledge to follow the evolution that the process of discovering and obtaining drugs has undergone in the mandatory curricular units, in this curricular unit must develop a critical spirit to find the solution to a problem related to the theme and the capacity for adequate expression, as well as argumentation through the preparation of reports, presentation and discussion of a solution to a problem.


The existence of the course unit of Planning and Sustainable Procurement of Pharmaceuticals is justified by the need to complement the content of the course units of Pharmaceutical Chemistry, generalist by nature, with a set of essential knowledge to accompany the Pharmaceutical Industry in the evolution that has undergone of new drugs.

 

 

 

Toxic Plants, Their Importance for Humans and Animals

MI244172 - ECTS

In the plant kingdom there are potentially 300 000 species, so the toxic effects of plants act as a defense mechanism against natural predators.

 

Plant toxins are secondary metabolites of plants that occur naturally in foods, feeds, weeds and ornamental plants and their chemical diversity is astonishing.

 

For a health professional (human or animal) it is increasingly important to have in-depth knowledge about toxic plants (from their botanical identification to antidotes (when available) and respective treatment).

Health Systems and Policies

MI135191 - ECTS To provide students with knowledge on health policies and healthcare systems organization on their different dimensions, with a particular focus on the Portuguese healthcare system and the contextualization of the pharmaceutical sector, in order to give them the necessary scientific bases and professional skills to intervene professionally in the healthcare system.

Project I

MI074172 - ECTS

This course unit aims to provide the student with the skills to execute, under guidance, an action plan in its strands, namely in:

  • Research and bibliographical interpretation;
  • Aims and strategies/applications to be applied;
  • Interpretation and discussion of the results obtained;
  • Writing of scientific report.

 

Within the scope of transversal competences, this Course Unit aims to contribute to the development of the following:

  • Cognitive Competencies: analytical, critical, reflective and creative thinking, namely in the preparation of the report;
  • Methodological Competencies: Time Management, Problem Solving Capacity, Learning Strategies and Planning Capability, in the execution of the project;
  • Social Competences: interpersonal communication, namely in the work presentation, and collaborative work related to the integration in the research team.

Project II

MI074173 - ECTS

Virology

MI074237 - ECTS

The objective of this curricular unit is to: i) study viruses as individual biological entities; ii) know the general aspects of the pathogenesis of viral infections; iii) know the diferent viral families and the viruses that cause human infection; iv) study the pathogenic role of these viruses, the clinical and epidemiological aspects of these infections, and their treatment, prevention and control measures; v) know the basic principles of the laboratory diagnosis of viral infections.

It is also intended to contribute to the development of the following transversal competences:

- Cognitive competences: analytical, critical, reflective and creative thinking;

- Methodological competences: time management and digital competencies;

- Social competences: interpersonal communication and collaborative work.

Clinical Biochemistry

MI074235 - ECTS

The theoretical programme aims to give a theoretical elementary training in the area of Clinical Biochemistry, the chemical and biochemical methods applied to the study of different pathologies, the related molecular mechanisms as well as the interpretation of analytical results in relation to diagnosis and treatment of diseases. In the laboratory programme, in parallel with the theoretical programme, it is emphasised the importance of a correct collection of samples, the interpretation and execution of a basic clinical biochemical laboratory study, as well as the correlation between the analytical results and the diagnosis and treatment of diseases.

Pharmaceutical Sciences

MI203297 - ECTS

This UC should contribute to the acquisition of knowledge and promote the development of attitudes and competences in the scientific areas Health Sciences / Physical Sciences / Natural Sciences / Technological Sciences / Social Sciences established under the terms of the optional UCs present in Table No. 1 of Order 7536/2023 (concerning the Curricular Structure of the integrated study cycle leading to a Master's degree in Pharmaceutical Sciences).

The specific objectives of this curricular unit (UC) correspond to the objectives of the university teaching UC that is credited by the Scientific Commission (ComC) of the Integrated Master in Pharmaceutical Sciences (MICF), or by commissions to which the ComC delegates competences for this. The accreditation of the training is dependent on the level of contribution of their learning outcomes to the objectives of the MICF.

Pharmaceutical Distribution

MI074162 - ECTS

Pharmaceutical Distribution Purpose: To provide general notions of Pharmaceutical Distributions with special focus on operational management and strategic planning of Pharmaceutical Distribution.

Industrial Pharmacy

MI075171 - ECTS

To familiarize students with the main characteristics of a pharmaceutical company, in particular, concerning its organization, functioning, quality management and legal framework.

To achieve these objectives, the student must spend 81 hours of work (3 ECTS x 27 hours) which included theoretical classes and practicals.

Compounding Pharmacy

MI075177 - ECTS

To provide students with a thorough knowledge on the technical, scientific and regulatory aspects underlying Compounding Pharmacy, in order to provide them the necessary scientific bases and professional skills on compounding and dispensing compounded medicines either at the Community or Hospital Pharmacy.

Pharmacology II

MI244140 - ECTS

The course unit (CU) of Pharmacology II is integrated within in a sequence of CUs, namely with Pharmacology I and a Pathophysiology and Pharmacotherapy I and II. Taken together, these CUs are intended to help the student to:

  1. Understand the mode of action of drugs in humans;
  2. Understand the factors that influence the permanence of drugs in the body and the methods that can be used to calculate and adjust doses and the dosage regimen that ensure the maintenance of appropriate concentrations to achieve the desired therapeutic effects;
  3. Understand the occurrence of adverse reactions and explain those arising from predictable pharmacodynamic responses;
  4. Understand interindividual variability in drug response as a function of genetic and non-genetic factors;
  5. Know the most widely explored pharmacological targets for therapeutic purposes, the most representative drugs in each group and the contexts in which they are clinically used;
  6. Understand the general aspects of the pathologies that are the main indications for each group of drugs.

In this context, the CU of Pharmacology II hasa global aim to capacitate the students with the necessary scientific knwledge, professional attitudes and technicl skills in order to develop, as independent professionals, activities that are part of the Pharmaceutical Act, namely the interpretation and evaliation of medical prescriptions; information on human medicines and communication among health preofessional and patientes/caregivers to promote the rational use of medicines; follow up the use of human medicines and medical devices.

As specific objectives, the CU of Pharmacology II aims to enable the student with consistent and critical pharmacological and pharmacotherapeutic knowledge, attitudes and technical skills in the areas of cardiovascular and endocrine pharmacology. Thus, in each chapter, key points will be selected in order to:

  1. Explain the different pathophysiological mechanisms of the diseases and the therapeutic aims of the various pharmacological and non-pharmacological interventions;
  2. Instruct the reference drugs of each therapeutic class;
  3. Instruct the historical development of reference drugs and the pharmacodynamic and pharmacokinetic limitations that have conditioned and / or will condition the appearance of new drugs from each group;
  4. To elucidate the basic pharmacodynamic activity resulting from acting on each target;
  5. Instruct the main pharmacological effects resulting from this activity;
  6. Instruct the present therapeutic indications and future perspectives of new drugs, or new indications.

Within the scope of transversal competences, this UC aims to contribute to the development of:

  • Cognitive skills: analytical, critical, reflective and creative thinking;
  • Methodological competences: careful selection of relevant information, time management and planning capacity;
  • Social skills: interpersonal communication (oral and written) and collaborative work.

Pathophysiology and Pharmacotherapy I

MI244241 - ECTS Pathophysiology and Pharmacotherapy I is a curricular unit (CU) integrated into a sequence of CUs that include Pharmacology I and II and Pathophysiology and Pharmacotherapy II. This sequence of CUs aims to be a core component of the General Objective of the Integrated Master in Pharmaceutical Sciences at the FFUP, once they provide the student with deep knowledge about the relationship drug/patient.Taken together, these CUs have the overall goal of helping the student to:
1. Understand the way drugs act in man;
2. Understand the factors that determine the permanence of the drugs in the body and know the methods that allow to calculate the doses and adjust the dosage regimens to ensure the maintenance of the adequate concentrations to obtain the desired therapeutic effects;
3. Understand the occurrence of adverse reactions and explain those arising from predictable pharmacodynamic responses;
4. Understand interindividual variability in response to drugs in functions of genetic and non-genetic factors.
5. To know the pharmacological targets most exploited for therapeutic purposes, the most representative drugs of each group and the contexts in which they are used clinically.
6. Understand the general aspects of the pathologies that are the main indications of each group of drugs.
7. Identify relevant information on new drugs, their mechanisms of action and pharmacological targets where they operate.

When considering the FIP Global Competency Framework v2, Pathophysiology and Pharmacotherapy I contributes to virtually all the competencies included in the Pharmaceutical Care competency cluster, namely 2.1 Assessment of medicines, 2.2 Dispensing, 2.4 Medicines, 2.5 Monitor medicines therapy, 2.6 Patient consultation and diagnosis, as well as competencies from other clusters like 1.3 Medicines information and advice, and enables students to a more effective Interprofessional collaboration and increases their Communication skills.



Lectures will be used for generic presentations of each of the themes, aiming to give the students an overview of each chapter that prepares them for autonomous learning and for a continuous education throughout their professional life.

In each chapter, key points will be selected to help the student:

1. To understand the pharmacodynamic fundamentals resulting from the performance in each target;
2. To know the main pharmacological effects resulting from this action, regardless of whether they are exploited for therapeutic purposes or can be classified as adverse reactions to the present therapeutic indications;
3. Know the historical context of your discovery
4. Understand the disease and the therapeutic objectives of the various pharmacological interventions.
5. To know the reference drugs of each class and the pharmacodynamic and pharmacokinetic limitations that conditioned and/or condition the appearance of new drugs in the group;
6. To know the present therapeutic indications and future perspectives of new drugs or new indications.

In this context, the curricular unit of Pathophysiology and Pharmacotherapy I has as specific objectives:
1. To help the student to obtain a pharmacological and pharmacotherapeutic knowledge consistent and critical, suitable for graduation in Pharmaceutical Sciences in the area of immunopharmacology;
2. To know the main groups of drugs used in the areas addressed, their mechanisms of action and adverse reactions as well as particularities about their clinical use.

Pharmaceutical Financial Management

MI244274 - ECTS

Hydrology and Hydrologic Analysis

MI234237 - ECTS

In the theoretical component, the most relevant aspects related to the indispensability of water for human development are addressed in a coherent and integrated way, in order to develop students’ ability to:

  • Know the origin, functions and different uses of water and its importance for human health.
  • Recognize the importance of an effective management of aquatic ecosystems, in order to combat the problems coming from global warming and demographic pressure, in particular the scarcity of fresh water and the pollution of water resources.
  • Evaluate and interpret the procedures associated with the various stages of the production processes of drinking water and wastewater treatment processes.
  • Recognize the basic concepts of hydrothermalism.

The laboratory component aims to develop students' analytical skills to:

  • physical-chemical characterization of drinking water.
  • assessment of the presence of chemical pollutants (pharmaceuticals included) in the different types of water.

In this way, students acquire a clear view of the importance of the challenges posed in this area of ​​knowledge and of the different areas in which their markedly interdisciplinary formation may constitute an important asset in the labor market.

Within the scope of transversal competences, this Curricular Unit aims to contribute to the development of:

  • Cognitive skills: analytical, critical, reflective and creative thinking;
  • Methodological skills: time management, planning skills and digital skills;
  • Social Skills: interpersonal communication and collaborative work.

Neuroscience

MI174269 - ECTS

Understand how the nervous system operates under normal and pathological conditions.
Acquire and update knowledge about the current state of neuroscience research.

Oncobiology

MI074260 - ECTS

At the end of the course, students should be able to:

  1. Recognise genetic, molecular and cellular alterations in cancer.
  2. Understand and explain the characteristics or "hallmarks" of cancer.
  3. Understand the difference between benign and malignant neoplasia.
  4. Understand the difference between sporadic, hereditary and familial cancer.
  5. Understand and discuss clinical problems related to early detection, diagnosis, prognosis and treatment.
  1. Know the biological rationale for precision therapies and immunotherapies.
  2. Recognise innovative therapeutic approaches.
  3. Know the biological rationale in the search for innovative diagnostic and prognostic biomarkers.
  1. Know and explain the risk factors and ways of preventing cancer.
  2. To contribute to information and literacy on cancer prevention and the promotion of health, a healthy lifestyle and quality of life.
  1. Learn about existing screening programs in Portugal, as well as the importance of early detection of cancer.
  1. Recognize the importance of the pharmacist in a multidisciplinary oncology team.
  2. Understand the importance of basic, translational and clinical research.

First Aids

MI073285 - ECTS Proper first aid is an asset to any citizen, particularly for the health professional.
 
This Course Unit aims at providing students technical and scientific knowledge in order to develop the necessary skills to good professional practices in trauma and medical emergency and other situations that the pharmacist is often confronted in his work, acting in every situation accordingly to the best practices and the Portuguese Integrated System of Medical Emergency (SIEM).

Project I

MI074172 - ECTS

This course unit aims to provide the student with the skills to execute, under guidance, an action plan in its strands, namely in:

  • Research and bibliographical interpretation;
  • Aims and strategies/applications to be applied;
  • Interpretation and discussion of the results obtained;
  • Writing of scientific report.

 

Within the scope of transversal competences, this Course Unit aims to contribute to the development of the following:

  • Cognitive Competencies: analytical, critical, reflective and creative thinking, namely in the preparation of the report;
  • Methodological Competencies: Time Management, Problem Solving Capacity, Learning Strategies and Planning Capability, in the execution of the project;
  • Social Competences: interpersonal communication, namely in the work presentation, and collaborative work related to the integration in the research team.

Project II

MI074173 - ECTS

Chemistry and Cosmetic Technology

MI244276 - ECTS

It is intended that students acquire a set of knowledge on concepts related with cosmetic products, namely the regulatory definition of cosmetic product and cosmetic ingredient. Students should be able to identify the main active and inactive ingredients, the most representative ingredients of each category, their functions, reactivities, structure-activity relationships, and applications in cosmetic products. The students should also know the principles of the pre-formulation of cosmetic products and recognize the main properties to be taken into account to select the composition of a product.They should also know and be able to use in silico tools and to execute in chemico e in vitro methods in the context of their physicochemical properties and evaluation of the biological activity and of human and environmental toxicity of cosmetic ingredients. They should know the main forms of presentation of cosmetic products and their typical compositions and know the respective quality parameters.   Students should know the principles of the rational development of cosmetic products and be able to apply the knowledge acquired to the formulation of a cosmetic product.

Integrative Therapies

MI244277 - ECTS

1- Provide students with adequate theoretical knowledge in the field of Integrative Therapies (IT), particularly those covered by Law No. 71/2013 of September 2, in order to equip them with the necessary skills for good professional performance in Community Pharmacy:

  • in pharmaceutical counseling;

  • in the acquisition of goods and services;

  • in the preparation, storage, conservation, and dispensing of Medicines and Other Health Products used by IT.

2- Provide students with the practical knowledge necessary for laboratory autonomy in the production of Homeopathic Medicines (according to the European Pharmacopoeia 10th Edition), namely:

  • in the preparation, quality control, labeling, and conservation of mother tinctures;

  • in the dynamization of mother tinctures and obtaining different homeopathic potencies;

  • in the impregnation of homeopathic potencies in granules, globules, and tablets;

  • in the proper packaging, labeling, and conservation of the prepared medicines.

Toxicology and Toxicological Analysis

MI075142 - ECTS The Toxicology and Toxicological Analysis Curricular Unit aims to develop the competence of students in Pharmaceutical Sciences in analyzing and understanding the toxicity mechanisms of xenobiotics with a high clinical, occupational and forensic impact, whether they are drugs, toxic substances or environmental and food contaminants. To this end, the fundamental and applied aspects of the analytical, clinical and forensic toxicology of xenobiotics are covered. It also aims to enable students to use the knowledge acquired in an integrated way to assess, predict and communicate the risk associated with xenobiotics.


Within the scope of transversal skills, this curricular unit aims to contribute to the development of the following:
  • Cognitive skills: analytical, critical, reflective and creative thinking;
  • Methodological skills: time management, planning skills and digital skills;
  • Social skills: interpersonal communication and collaborative work.

Mechanistic Toxicology

MI074234 - ECTS

Main Learning Objectives: that the students develop their abilities to:

  • Analyse and interpret the mechanisms associated with the toxicity of xenobiotics, as drugs, toxics or environmental and food contaminants;
  • Assess, predict and communicate risks associated with xenobiotics.

 
Within the scope of transversal competences, this Course Unit aims to contribute to the development of:

  • Cognitive Competencies: analytical, critical, reflective and creative thinking;
  • Methodological skills: time management, planning capacity and digital competencies;
  • Social Competences: interpersonal communication and collaborative work.

Pharmaceutical Care

MI075188 - ECTS

Main objetives
It is expected that students understand Pharmaceutical Care as the new philosophy of pharmacists professional practice and that at the end of this course, students will be able to:

a) understand the concept of Pharmaceutical Care and the different assistencial activities of the pharmacist care centered on the patient.

b) gain theoretical and practical skills to be able to carry them out.

 
Learning objectives:

At the end of the course it is expected that students will be able to:

1. Understand why medicines are responsible for increased morbidity and mortality
2. Explain the role of the pharmacist in the reduction of morbidity and mortality related to medicines
3. Define and describe the importance of pharmaceutical care for both patients and pharmacists
4. Identify which patients would benefit the most from pharmaceutical care
5. Perform directed drug/disease information searches in reliable databases, critically evaluate information and apply it to specific situations in simulation scenarios or in work with real patients
6. Effectively communicate with patients, caregivers and health professionals
7. Collect data using a systematic approach
8. Identify drug-related needs of patients
9. Identify drug-related problems and medication associated negative outcomes
10. Prioritize and solve drug-related problems/medication associated negative outcomes adequating different pharmaceutical interventions and evaluate their results
11. Develop and document a pharmaceutical care plan
12. Formulate and provide health educational interventions appropriated to the patient (or community) needs
13. Refer patients to other health professionals, when appropriate



 

Pathophysiology and Pharmacotherapy II

MI245143 - ECTS The Physiopathology and Pharmacotherapy II is part of a sequence of UCs that include Pharmacology I and II and Physiopathology and Pharmacotherapy I.

As a whole, these UCs have the general objective of learning helping the student to:

  1. Understand the way in which drugs work in humans.
  2. Understand the factors that condition the permanence of drugs in the body and to know the methods that allow to calculate the doses and adjust the dosage regimens to guarantee the maintenance of the appropriate concentrations to obtain the desired therapeutic effects.
  3. Understand the occurrence of adverse reactions and explain those resulting from predictable pharmacodynamic responses.
  4. Understand the inter-individual variability in response to drugs in function of genetic and non-genetic factors.
  5. To know the most explored pharmacological targets for therapeutic purposes, the most representative drugs in each group and the contexts in which they are used clinically.
  6. Understand the general aspects of the pathologies that are the main indications of each group of drugs.



Theoretical teaching will be used for generic presentations of each of the themes, seeking to give students a global view of each chapter that prepares them for autonomous learning and for continuous updating throughout their professional life. Thus, in each chapter, the key points that help the student to:

1. Understand the pharmacodynamic fundamentals resulting from the performance in each target;

2. Know the main pharmacological effects resulting from this action, regardless of whether they are explored for therapeutic purposes or may be classified as adverse reactions to the current therapeutic indications;

3. Understand the disease and the therapeutic objectives of the various pharmacological interventions;

4. To know the reference drugs of each class and the pharmacodynamic and pharmacokinetic limitations that have conditioned and/or will condition the appearance of new drugs in the group;

5. To know the current therapeutic indications and future perspectives of new drugs or new indications.


In this context, the curricular unit of Pathophysiology and Pharmacotherapy II has as specific objectives, to assist the student to obtain a pathophysiological and pharmacotherapeutic knowledge, consistent and critical, suitable for graduation in Pharmaceutical Sciences in the areas of cancer and infection; special protocols used in the treatment of chronic infectious diseases and associated symptoms; to know the main groups of drugs used in the areas covered, their mechanisms of action and adverse reactions, as well as particularities about their clinical use.

Hydrology

MI075141 - ECTS

In the theoretical component, the most relevant aspects related to the indispensability of water for human development are addressed in a coherent and integrated way, in order to develop students’ ability to:

  • Know the origin, functions and different uses of water and its importance for human health.
  • Recognize the importance of an effective management of aquatic ecosystems, in order to combat the problems coming from global warming and demographic pressure, in particular the scarcity of fresh water and the pollution of water resources.
  • Evaluate and interpret the procedures associated with the various stages of the production processes of drinking water and wastewater treatment processes.

The laboratory component aims to develop students' analytical skills to:

  • physical-chemical characterization of drinking water.
  • assessment of the presence of chemical pollutants (pharmaceuticals included) in the different types of water.

In this way, students acquire a clear view of the importance of the challenges posed in this area of ​​knowledge and of the different areas in which their markedly interdisciplinary formation may constitute an important asset in the labor market.

Within the scope of transversal competences, this Curricular Unit aims to contribute to the development of:

  • Cognitive skills: analytical, critical, reflective and creative thinking;
  • Methodological skills: time management, planning skills and digital skills;
  • Social Skills: interpersonal communication and collaborative work.

History of Pharmacy, Deontology and Legislation

MI075138 - ECTS

The students should aquire an integrated vision of the History of Pharmaceutical Sciences, developping competences that help him to understand the knowledges learned during the obtention of the master degree  according to the evolution of mankind, specially in what concerns the causes and the treatemnt of diseases.

Legislation and Regulatory Affairs of Medicinal Products

MI075179 - ECTS

To Understand why medicines must  be authorized and the design of the marketing authorization system.

To Know the terminology and concepts used at national and European level in the area of drug law and regulation, namely in pharmaceutical development,  and validation of methods and processes.

To Know and understand the regulation of aspects associated with the material flows, preparation and control of medicinal products for human or veterinary use, as well as with the evaluation of stability and definition of shelf life.

 

Public Health

MI075140 - ECTS

Public health aims to study the health of populations, understand the relationship between exposure (risk and intervention) and its consequences on the health of populations, program interventions to improve the global health. The Public Health has a mission directed to the education of populations, promotion and protection of health, care and treatment of the disease, and damage rehabilitation.

Toxicology and Toxicological Analysis

MI245144 - ECTS

The unit has as principal objective developing the competences of the students in the analysis and understanding of the mechanisms of toxicity of xenobiotics of high clinical, occupational and forensic relevance. For this purpose, the fundamental and applied, analytical, clinical, and forensic aspects of solvents, metals, drugs of abuse and pesticides will be studied. It is also sought that the  students are capable of using the acquired knowledge in an integrated fashion for risk assessment and for risk communication.

Training Period for the Pharmaceutical Sciences Master Degree

MI075243 - ECTS

 

The curricular internship aims to ensure adequate training for pharmaceutical practice in pharmacies (community and hospital), ensuring that it will be performed in a competent and responsible manner, namely in its technical and deontological aspects. It is regulated by Directive 2013/55/​​EU and by Regulation No. 706/2018 and Resolution 2272-F/2007 of the UPorto Rectory.

The internship is an inherent part of the MICF study plan, and its conclusion is an indispensable condition for obtaining a Master's degree in Pharmaceutical Sciences. It is at this stage that, after 9 semesters of theoretical and laboratory training, a large part of the skills inherent to the pharmacist become effective, in a context of professional practice and in view of the challenges inherent to it.

It is mandatory for 6 months and takes place in Pharmacies open to the public or in Pharmaceutical Services of central or district Hospitals in Portugal, with protocols signed with the FFUP, or under cooperation protocols with similar European entities, always under the guidance of monitors pharmacists at the internship locations and Advisor teatchers at FFUP.

It is intended that the student recognizes the relationship between health institutions and health professionals, with each other and with the population, acquire autonomy in the ability to understand, integrate and solve technical, scientific and ethical professional problems, which integrate the activities of the “Pharmaceutical Act” (Article 75, Law No. 131/2015), thus complementing the activities that were previously developed in the academic component of the MICF, namely:

a) Development and preparation of pharmaceutical forms of medicines;
b) Registration, manufacture and control of medicines for human and veterinary use and medical devices
e) Preparation, control, selection, acquisition, storage and dispensing of medicines for human and veterinary use and medical devices in pharmacies open to the public, hospital pharmaceutical services and private pharmaceutical services of any other public and private entities, without prejudice to the regime of distribution of non-prescription drugs to the public outside pharmacies, under the terms of the respective legislation;
f) Preparation of antiseptic solutions, disinfectants and intravenous mixtures;
g) Interpretation and evaluation of medical prescriptions;
h) Information and consultation on medicines for human and veterinary use, medical devices, subject and not subject to medical prescription, with health professionals and patients, in order to promote their correct use;
i) Monitoring, surveillance and control of the distribution, dispensing and use of medicines for human and veterinary use, medical devices;
j) Monitoring of drugs, including the determination of pharmacokinetic parameters and the establishment of individualized dosing schedules;
k) Collection of biological products, execution and interpretation of clinical analyzes and determination of serum level

The internship is fully aligned with the competencies defined in the document “FIP Global Competency Framework” for the early pharmacist's professional career, namely:

1. Pharmaceutical Public Health (Emergency response, Health promotion, Medicines information and advice)
2. Pharmaceutical Care (assessment and compounding medicines, dispensing, monitor medicines, patient consultation and diagnosis,
3. Organization and management
4. Professional / personal competencies

Additionally, and in order to stimulate the constant search for improvement in the internship pharmacies, in the relations with the users, with the community and with the health professionals, as well as the recognition of the continuous need for training, students are asked to develop activities and projects that contribute to the better use of medicines and services, for the identification, implementation and monitoring of new services, according to local needs, propose and implement education strategies for the health of the population, among others, in close alignment with the orientation 3.3.1 of the FIP. These activities are mandatory, must be well supported from a scientific point of view, are an integral part of the internship report and are presented and defended in public exams to obtain the master's degree.

 

Recommend this page Top
Copyright 1996-2025 © Faculdade de Farmácia da Universidade do Porto  I Terms and Conditions  I Acessibility  I Index A-Z  I Guest Book
Page created on: 2025-06-16 at 09:02:49 | Acceptable Use Policy | Data Protection Policy | Complaint Portal