Organic Chemistry I
Keywords |
Classification |
Keyword |
OFICIAL |
Physical Sciences (Chemistry) |
Instance: 2012/2013 - 1S
Cycles of Study/Courses
Acronym |
No. of Students |
Study Plan |
Curricular Years |
Credits UCN |
Credits ECTS |
Contact hours |
Total Time |
MIEQ |
105 |
Syllabus |
1 |
- |
5 |
70 |
135 |
Teaching language
Portuguese
Objectives
At the end of the semester, students should:
I- be capable of identifying and representing organic molecules;
II- be acquainted with the reactivity of organic compounds;
III- be capable of creating synthesis strategies of complex organic compounds by simple compounds.
This course aims to acquaint students with technical knowledge of underlying sciences and understanding, not only in the field of engineering, but also in other fields.
This course also aims to develop students’ scientific and critical reasoning.
Program
Theoretical program
1. Structure of organic molecules: molecular and structural formulas
2. Functional groups and families of organic compounds; Name of the organic compounds.
3. Structure of functional groups and physical properties of organic compounds: melting and boiling point; solubility.
4. Introduction to infrared spectroscopy: identification of functional groups.
5. Stereochemistry: Conformacional Analysis; Cis-trans isomerism; Chirality and optical activity.
6. Chemical reactivity; Reactions of organic compounds; Reactive intermediates (carbocation, carbanion, free radicals): structure and relative stability.
7. Alkane reaction: combustion; homolytic substitution; halogenation; regioselective bromination.
8. Nucleophilic substitution at saturated carbon; Duality of mechanism: SN2 and SN1 reactions ; Kinetics, Factors which affect velocity of reactions of SN2 and SN1.
9. Elimination reactions; Elimination mechanisms: E2 and E1; Elimination vs. substitution; Stereochemistry: elimination anti and syn; alkene and alkyne formation;
10. Reactions of electrophilic addition and multiple connections carbon-carbon; Addition mechanism; Orientation and reactivity; Markovnikov’s rule; Additions to alkenes and alkynes; Alkene oxidation; Alkene polymerization.
Laboratory Program
1. Purification methods of organic compounds: multiple extraction liquid-liquid and continuous extraction solid-liquid; crystallization; simple distillation; analytical and preparative chromatography.
2. Purity criteria of organic compounds: melting point, boiling point, chromatography and infrared spectra.
3. Practical assignments:
A1- Extraction and crystallization: isolation of acetylsalicylic acid.
A2- Preparative and analytical chromatography: separation of vanillin and acetophenone.
A3- Electrophilic addition- Halogenation of alkenes.
A4- Unimolecular nucleophilic substitution (SN1).
Mandatory literature
Solomons, T. W. Graham;
Organic Chemistry. ISBN: 0-471-19095-0
Carey, Francis A;
Organic chemistry. ISBN: 0-07-115148-6
Margarida M. S. M. Bastos; Quimica Orgânica I - Documentação 2009-2010
Complementary Bibliography
Morrison, R.;
Química orgânica. ISBN: 972-31-0513-6
Vollhardt, K. Peter C.;
Organic chemistry. ISBN: 0-7167-4374-4
Teaching methods and learning activities
General theoretical-practical classes will be based on the presentation of theoretical-practical themes (2, 5 hours per week). They will be supported by data show and transparencies, and they will be based on problem solving. Theoretical-practical classes (1 hour per week) will be mainly based on problem solving.
Whenever possible, concepts will be explained by laboratory assignments (1,5 hour per week).
Software
ChemDraw Ultra
Evaluation Type
Distributed evaluation with final exam
Assessment Components
Description |
Type |
Time (hours) |
Weight (%) |
End date |
Attendance (estimated) |
Participação presencial |
75,00 |
|
|
|
Total: |
- |
0,00 |
|
Eligibility for exams
Students have to attend to a minimum number of classes and achieve a minimum grade of 9,5 out of 20 in laboratory assignments. This assessment will be based on how students carried out the assignments, on the analysis of their reports and on a laboratorial test.
Attendance and the mark of the practical component of the course will be valid for two years.
Calculation formula of final grade
The theoretical component of the course will be assessed as follows:
TC=0,1xQ+0,1xSH+0,8xFE
Q- Questionnaires
FE- Final Exam
TC- Theoretical component
SH - Student Homework
FM= 0,75xTC+ 0,25xPC
FM- Final Mark
TC- Theoretical component
PC- Practical component
Examinations or Special Assignments
Students, who do not need to attend classes and were not admitted to exams, have to attend a practical exam and a theoretical assignment about practical concepts of the last laboratory class.
Special assessment (TE, DA, ...)
An exam and practical assignments
Classification improvement
Students can only improve the grade of the theoretical component of the course (75% of the final mark). The exam will take place at recurso season.