Terahertz spectroscopy for the study of paraffin-embedded gastric cancer samples

• Type: Article in International Scientific Journal
• Date: 2015

Authors

Faustino Wahaia (Author) Other; Irmantas Kasalynas (Author) Other; Dalius Seliuta (Author) Other; Gediminas Molis (Author) Other; Andrzej Urbanowicz (Author) Other; Catia Carvalho C Silva (Author) Other; Fatima Carneiro (Author) Other; Gintaras Valusis (Author) Other; Pedro L Granja (Author) FEUP

Journal

Title: Journal of Molecular Structure

Vol. 1079

Pages: 391-395

ISSN: 0022-2860

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 18 Citations

Scopus - 20 Citations

Scientific classification

FOS: Natural sciences > Chemical sciences

Other information

Authenticus ID: P-009-YC9

DOI: 10.1016/j.molstruc.2014.09.002

Abstract (EN): Terahertz (THz) spectroscopy constitute promising technique for biomedical applications as a complementary and powerful tool for diseases screening specially for early cancer diagnostic. The THz radiation is not harmful to biological tissues. As increased blood supply in cancer-affected tissues and consequent local increase in tissue water content makes THz technology a potentially attractive. In the present work, samples of healthy and adenocarcinoma-affected gastric tissue were analyzed using transmission time-domain THz spectroscopy (THz-TDS). The work shows the capability of the technique to distinguish between normal and cancerous regions in dried and paraffin-embedded samples. Plots of absorption coefficient alpha and refractive index n of normal and cancer affected tissues, are presented and the conditions for discrimination between normal and affected tissues are discussed.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5