Terahertz spectroscopy for the study of paraffin-embedded gastric cancer samples

• Tipo: Artigo em Revista Científica Internacional
• Data: 2015

Autores

Faustino Wahaia (Autor) Outra; Irmantas Kasalynas (Autor) Outra; Dalius Seliuta (Autor) Outra; Gediminas Molis (Autor) Outra; Andrzej Urbanowicz (Autor) Outra; Catia Carvalho C Silva (Autor) Outra; Fatima Carneiro (Autor) Outra; Gintaras Valusis (Autor) Outra; Pedro L Granja (Autor) FEUP

Revista

Título: Journal of Molecular Structure

Vol. 1079

Páginas: 391-395

ISSN: 0022-2860

Editora: Elsevier

Indexação

ISI Web of Knowledge - 18 Citações

Scopus - 20 Citações

Classificação Científica

FOS: Ciências exactas e naturais > Química

Outras Informações

ID Authenticus: P-009-YC9

DOI: 10.1016/j.molstruc.2014.09.002

Abstract (EN): Terahertz (THz) spectroscopy constitute promising technique for biomedical applications as a complementary and powerful tool for diseases screening specially for early cancer diagnostic. The THz radiation is not harmful to biological tissues. As increased blood supply in cancer-affected tissues and consequent local increase in tissue water content makes THz technology a potentially attractive. In the present work, samples of healthy and adenocarcinoma-affected gastric tissue were analyzed using transmission time-domain THz spectroscopy (THz-TDS). The work shows the capability of the technique to distinguish between normal and cancerous regions in dried and paraffin-embedded samples. Plots of absorption coefficient alpha and refractive index n of normal and cancer affected tissues, are presented and the conditions for discrimination between normal and affected tissues are discussed.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 5