Silica-Based Nanomaterials for Diabetes Mellitus Treatment

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2023

Autores

Marinheiro, D (Autor) Outra; Martel, F (Autor) FMUP; Ferreira, BJML (Autor) Outra; Daniel-da-Silva, AL (Autor) Outra

Revista

Título: Bioengineering

Vol. 10 Nº 3

Página Final: 40

Editora: MDPI

Indexação

ISI Web of Knowledge - 0 Citações

Scopus

Outras Informações

ID Authenticus: P-00X-VCF

DOI: 10.3390/bioengineering10010040

Abstract (EN): Diabetes mellitus, a chronic metabolic disease with an alarming global prevalence, is associated with several serious health threats, including cardiovascular diseases. Current diabetes treatments have several limitations and disadvantages, creating the need for new effective formulations to combat this disease and its associated complications. This motivated the development of therapeutic strategies to overcome some of these limitations, such as low therapeutic drug bioavailability or poor compliance of patients with current therapeutic methodologies. Taking advantage of silica nanoparticle characteristics such as tuneable particle and pore size, surface chemistry and biocompatibility, silica-based nanocarriers have been developed with the potential to treat diabetes and regulate blood glucose concentration. This review discusses the main topics in the field, such as oral administration of insulin, glucose-responsive devices and innovative administration routes.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 23