SOLID LIPID NANOPARTICLES: CLASSICAL METHODS OF LAB PRODUCTION

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2011

Autores

Souto, EB (Autor) Outra; Severino, P (Autor) Outra; Santana, MHA (Autor) Outra; Pinho, SC (Autor) Outra

Revista

Título: Quimica Nova

Vol. 34 Nº 3

Páginas: 1762-1769

ISSN: 0100-4042

Editora: Sociedade Brasileira de Quimica

Indexação

ISI Web of Knowledge - 20 Citações

Outras Informações

ID Authenticus: P-002-ZE0

Abstract (EN): SOLID LIPID NANOPARTICLES: CLASSICAL METHODS OF LAB PRODUCTION. Solid lipid nanoparticles have been extensively investigated as drug delivery systems. These colloidal systems have major advantages compared to others more traditional. Reported advantages include sustained release, ability to solubilize lipophilic drugs, increased physical and chemical stability of labile molecules, decreased unwanted side-effects showing lower toxicity, and scale up facilities. This paper aims at reviewing the traditional methods of solid lipid nanoparticles production, such as fusion-emulsification (hot and cold), solvent evaporation-emulsification and microemulsion, dealing with the main technological parameters that influence the quality properties of solid lipid nanoparticles.

Idioma: Português

Tipo (Avaliação Docente): Científica

Nº de páginas: 8