Highlighting Immune System and Stress in Major Depressive Disorder, Parkinson's, and Alzheimer's Diseases, with a Connection with Serotonin

• Tipo: Artigo em Revista Científica Internacional
• Data: 2021

Autores

Correia, AS (Autor) Outra; Armando Cardoso (Autor) FMUP; Nuno Vale (Autor) FMUP

Revista

Título: International Journal Of Molecular Sciences

Vol. 22

Página Final: 8525

ISSN: 1661-6596

Editora: MDPI

Indexação

ISI Web of Knowledge - 5 Citações

Outras Informações

ID Authenticus: P-00V-85Y

DOI: 10.3390/ijms22168525

Abstract (EN): There is recognition that both stress and immune responses are important factors in a variety of neurological disorders. Moreover, there is an important role of several neurotransmitters that connect these factors to several neurological diseases, with a special focus in this paper on serotonin. Accordingly, it is known that imbalances in stressors can promote a variety of neuropsychiatric or neurodegenerative pathologies. Here, we discuss some facts that link major depressive disorder, Alzheimer's, and Parkinson's to the stress and immune responses, as well as the connection between these responses and serotonergic signaling. These are important topics of investigation which may lead to new or better treatments, improving the life quality of patients that suffer from these conditions.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 18