Abstract (EN):
Biomembrane models built at the interface between two immiscible
electrolytes (ITIES) are useful systems to study phenomena
of biological relevance by means of their electrochemical
processes. The unique properties of ITIES allow one either
to control or measure the potential difference across the biomimetic
membranes. Herein we focus on phospholipid monolayers
adsorbed at liquid–liquid interfaces, and besides discussing
recent developments on the subject, we describe electrochemical
techniques that can be used to get insight on the interfacial processes and electrostatic properties of phospholipid
membranes at the ITIES. In particular, we examine the electrochemical
and physicochemical properties of (modified) phospholipid
monolayers and their interaction with other biologically
relevant compounds. The use of liquid–liquid electrochemistry
as a powerful tool to characterize drug properties is
outlined. Although this review is not a survey of all the work in
the field, it provides a comprehensive referencing to current
research.
Idioma:
Inglês
Tipo (Avaliação Docente):
Científica
Contacto:
helder.santos@helsinki.fi