Picocyanobacteria From a Clade of Marine Cyanobium Revealed Bioactive Potential Against Microalgae, Bacteria, and Marine Invertebrates

• Tipo: Artigo em Revista Científica Internacional
• Data: 2015

Autores

Maria Sofia Costa (Autor) Outra; Margarida Costa (Autor) Outra; Vitor Ramos (Autor) Outra; Pedro N Leao (Autor) Outra; Aldo Barreiro (Autor) Outra; Vitor Vasconcelos (Autor) FCUP; Rosario Martins (Autor) Outra

Revista

Título: Journal of Toxicology and Environmental Health - Part A

Vol. 78

Páginas: 432-442

ISSN: 1528-7394

Editora: Taylor & Francis

Indexação

ISI Web of Knowledge - 25 Citações

Scopus - 24 Citações

Classificação Científica

FOS: Ciências médicas e da saúde > Ciências da saúde

Outras Informações

ID Authenticus: P-00A-9DZ

DOI: 10.1080/15287394.2014.991466

Abstract (EN): The production of bioactive compounds either toxic or with pharmacological applications by cyanobacteria is well established. However, picoplanktonic forms within this group of organisms have rarely been studied in this context. In this study, the toxicological potential of picocyanobacteria from a clade of marine Cyanobium strains isolated from the Portuguese coast was examined using different biological models. First, strains were identified by applying morphological and molecular approaches and cultured under lab conditions. A crude extract and three fractions reflecting a preliminary segregation of lipophilic metabolites were tested for toxicity with the marine microalga Nannochloropsis sp., the bacteria Pseudomonas sp., the brine shrimp Artemia salina, and fertilized eggs of the sea urchin Paracentrotus lividus. No significant apparent adverse effects were noted against Artemia salina. However, significant adverse effects were found in all other assays, with an inhibition of Nannochloropsis sp. and Pseudomonas sp. growth and marked reduction in Paracentrotus lividus larvae length. The results obtained indicated that Cyanobium genus may serve as a potential source of interesting bioactive compounds and emphasize the importance of also studying smaller picoplanktonic fractions of marine cyanobacteria.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 11