Microalgal compounds modulate carcinogenesis in the gastrointestinal tract

• Tipo: Artigo em Revista Científica Internacional
• Data: 2013

Autores

Helena M. Amaro (Autor) Outra; Rita Barros (Autor) Outra; A. Catarina Guedes (Autor) FCUP; I. Sousa-Pinto (Autor) FCUP; F. Xavier Malcata (Autor) FEUP

Revista

Título: Trends in Biotechnology

Vol. 31 Nº 2

Páginas: 92-98

ISSN: 0167-7799

Editora: Elsevier

Indexação

ISI Web of Knowledge - 29 Citações

ISI Web of Science

Scopus - 45 Citações

Classificação Científica

FOS: Ciências exactas e naturais > Ciências biológicas

Outras Informações

ID Authenticus: P-002-0SB

DOI: 10.1016/j.tibtech.2012.11.004

Abstract (EN): Gastrointestinal cancers rank second in overall cancer-related deaths. Carotenoids, sulfated polysaccharides, and polyunsaturated fatty acids (PUFAs) from microalgae exhibit cancer chemopreventive features at different stages of carcinogenesis. For instance, sulfated polysaccharides bear a prophylactic potential via blocking adhesion of pathogens to the gastric surface, whereas carotenoids are effective against Helicobacter pylori infection. This effect is notable because H. pylori has been targeted as the primary cause of gastric cancer. Recent results on antitumor and antibacterial compounds synthesized by microalgae are reviewed here, with an emphasis on their impact upon H. pylori infection and derived pathologies accompanying the progression of gastric carcinogenesis.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 7