The Role of Anthocyanins in Alleviating Intestinal Diseases: A Mini Review

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2024

Autores

Liu, Y (Autor) Outra; Iva Fernandes (Autor) FCUP; Mateus, N (Autor) Outra; Oliveira, H (Autor) Outra; Han, FL (Autor) Outra

Revista

Título: Journal of Agricultural and Food Chemistry

Vol. 72

Páginas: 5491-5502

ISSN: 0021-8561

Editora: American Chemical Society

Indexação

ISI Web of Knowledge - 0 Citações

Scopus - 0 Citações

Outras Informações

ID Authenticus: P-010-52Y

DOI: 10.1021/acs.jafc.3c07741

Abstract (EN): Anthocyanins are phytonutrients with physiological activity belonging to the flavonoid family whose transport and absorption in the human body follow specific pathways. In the upper gastrointestinal tract, anthocyanins are rarely absorbed intact by active transporters, with most reaching the colon, where bacteria convert them into metabolites. There is mounting evidence that anthocyanins can be used for prevention and treatment of intestinal diseases, including inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and colorectal cancer (CRC), through the protective function on the intestinal epithelial barrier, immunomodulation, antioxidants, and gut microbiota metabolism. Dietary anthocyanins are summarized in this comprehensive review with respect to their classification and structure as well as their absorption and transport mechanisms within the gastrointestinal tract. Additionally, the review delves into the role and mechanism of anthocyanins in treating common intestinal diseases. These insights will deepen our understanding of the potential benefits of natural anthocyanins for intestinal disorders.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 12