The Bioactivity of Pomegranate: Impact on Health and Disease

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2011

Autores

Ana Faria (Autor) FCUP; Conceicao Calhau (Autor) FMUP

Revista

Título: Critical Reviews in Food Science and Nutrition

Vol. 51 Nº 7

Páginas: 626-634

ISSN: 1040-8398

Editora: Taylor & Francis

Indexação

ISI Web of Knowledge - 32 Citações

ISI Web of Science

Scopus - 47 Citações

Pubmed / Medline

Classificação Científica

FOS: Ciências agrárias > Outras ciências agrárias

CORDIS: Ciências da Saúde > Ciências farmacológicas

Outras Informações

ID Authenticus: P-002-YA2

DOI: 10.1080/10408391003748100

Abstract (EN): The aim of the present review is to discuss the cumulative evidence that suggests that pomegranate consumption possesses a diverse array of biological actions and may be helpful in the prevention of some inflammatory-mediated diseases including cancer. The pomegranate fruit can be divided into at least three parts-seeds, peel, and juice. All these components have been studied for their antioxidant properties in a chemoprevention approach. Pomegranate exerts antiproliferative, anti-invasive, and antimetastatic effects, induces apoptosis through modulation of Bcl-2 proteins, increases p21 and p27, and downregulates cyclin-cdk network. In addition, pomegranate inhibits the activation of inflammatory pathways including, but not limited to, the NF kappa-B pathway. Anti-cancer effects with the most impressive data have been demonstrated so far in prostate cancer.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Notas: <a href="http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS&DestLinkType=FullRecord&KeyUT=000293839700004 ">Indexado na Web of Science</a> Epub 2011 Mai 06

Nº de páginas: 9