Animal Cytogenetics

Code:

MV113

Acronym:

CA

Keywords
Classification	Keyword
OFICIAL	Basic Sciences

Instance: 2024/2025 - 1S (of 16-09-2024 to 10-01-2025)

Active?	Yes
Web Page:	http://sigarra.up.pt/icbas/disciplinas_geral.FormView?P_CAD_CODIGO=MV113&P_ANO_LECTIVO=2009/2010&P_PERIODO=1S
Responsible unit:	Microscopy
Course/CS Responsible:	Integrated Masters Degree in Veterinary Medicine

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MIMV	83	Official Study Plan	1	-	2	20	54

Teaching language

Portuguese

Objectives

The student must acquire the following basic cytogenetic capacities/knowledge: morphological, structural and functional organization of chromosomes, mutations that can change this organization and application of these knowledge to veterinary pathology, with a particular incidence in fertility problems and tumoral situations.

Learning outcomes and competences

It is expected that the students acquire the fundamental basis of cytogenetics in order to apply them in future programs of advanced genetics.

Working method

Presencial

Program

Theorical programme: Cell Cycle: modifications during mitosis and meiosis. Chromosome morphology and structure. Euchromatin and heterochromatin. Numerical and structural chromosome abnormalities. Sex chromosomes. Sexual determination and sexual diferentiation. Mutagenesis. Genotoxic agents. Chromosome instability and cancer. Practical programme: basic cytogenetic techniques. Classification and identification of chromosomes in the karyotype. Chromosome banding techniques. In situ hybridization techniques applied to cytogenetics. Techniques for comparative genomics. Cytogenetic nomenclature and karyotype description with balanced and non-balanced chromosome abnormalities. Analysis of the consequences of balanced chromosomal abnormalities (inversions and translocations) in gamete segregation.

Mandatory literature

Halnan Clive R. E. ed.; Cytogenetics of animals. ISBN: 0-85198-629-3
Azevedo Carlos 340; Biologia celular e molecular. ISBN: 972-757-354-1
Nicholas F. W.; Introduction to veterinary genetics. ISBN: 1-4051-0633-6

Complementary Bibliography

Lacadena Juan-Ramón; Citogenética. ISBN: 84-89365-58-X
Nicholas F. W.; Veterinary genetics. ISBN: 0-19-857569-6
O.Brien Stephen J. 340; Atlas of mammalian chromosomes. ISBN: 0-471-35015-X

Teaching methods and learning activities

Theory and Practice (laboratorial and theorico-practical) with audiovisual support and documents

Evaluation Type

Evaluation with final exam

Assessment Components

Designation	Weight (%)
Exame	100,00
Total:	100,00

Amount of time allocated to each course unit

Designation	Time (hours)
Estudo autónomo	34,00
Frequência das aulas	20,00
Total:	54,00

Eligibility for exams

Not exceed the absence limit corresponding to 25% of the classes provided

Calculation formula of final grade

Final Exam with different types of questions (choice of true or false, multiple choice questions with predefined key, questions with correspondences) and questions for a short answer.  Wrong answers do not discount.

Classification improvement

Final exam

Observations

Evaluation only made by final examination