Complements of Molecular Biology

Code:

CB4000

Acronym:

CB4000

Keywords
Classification	Keyword
OFICIAL	Biological Sciences

Instance: 2018/2019 - 1S

Active?	Yes
Responsible unit:	Molecular Biology
Course/CS Responsible:	Master in Biochemistry

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
M:BQ	28	Plano de Estudos do MBIOQ_2013-2014	1	-	6	56	162

Teaching language

Suitable for English-speaking students

Objectives

The aim is to provide students advanced skills to analyze and solve problems in diverse areas such as functional and structural genomics, cell division, protein sorting in the eukaryotic cell (ER, mitochondria and peroxisomes as case studies), protein regulation by ubiquitin and ub-like molecules (e.g., SUMO), and the molecular biology of complex phenomena such as angiogenesis.

Learning outcomes and competences

Acquisition of advanced knowledge on a few topics of Molecular Biology. Capacity to dissect a scientific paper and present it to a small audience. 

 

Working method

Presencial

Program

 

Functional and structural genomics

RNA Biology

Protein regulation by Ubiquitin and UbLs

Architecture and regulation of the NF-kB system

The secretory pathway

The molecular and cellular biology of mitochondria

Organelle Biogenesis (the peroxisome)

Molecular bases of angiogenesis

Cell Division

Model Organisms - studying human diseases

Mandatory literature

Alberts Bruce; Molecular biology of the cell

Comments from the literature

 

A free edition of Molecular Biology of the Cell (IV Ed.) 2002 by Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter can be found at http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mboc4.TOC&depth=2.

All of the topics addressed in this course have a very specific bibliography (scientific papers).

Any recent textbook on Molecular and Cellular Biology may also be used with the purpose of helping the student acquiring a general perspective on a given topic.

Teaching methods and learning activities

 

Lectures on each of the selected topics. Presentation and discussion of articles (2-4 per topic) by the students.

 

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Designation	Weight (%)
Exame	75,00
Prova oral	25,00
Total:	100,00

Amount of time allocated to each course unit

Designation	Time (hours)
Apresentação/discussão de um trabalho científico	5,00
Estudo autónomo	28,00
Frequência das aulas	56,00
Total:	89,00

Eligibility for exams

Presence in 3/4 of TP classes

Calculation formula of final grade

Students are evaluated by

- Final written exam (grade: 15 in 20)

- presentation and discussion of a scientific paper on a selected subject (grade: 5 in 20)