Biochemistry II

Code:

Q3024

Acronym:

Q3024

Level:

300

Keywords
Classification	Keyword
OFICIAL	Chemistry

Instance: 2017/2018 - 1S

Active?	Yes
Responsible unit:	Molecular Biology
Course/CS Responsible:	Bachelor in Biochemistry

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
L:BQ	72	Official Study Plan	3	-	9	70	243

Teaching language

Português - Suitable for English-speaking students

Objectives

Students should be able to acquire skills that enable them to describe metabolic situations both in normal cells or associated with pathologies. They should know the main steps of metabolic regulation mediated by signaling molecules

Learning outcomes and competences

Students should be able to acquire skills that enable them to describe metabolic situations both in normal cells or associated with pathologies. Thus they should be able to identify metabolic pathways that are affected in metabolic diseases. They should be able to have an integrated approach of metabolism either cell and organ. At the end of attending the unit besides becoming familiar with metabolic pathways they should have acquire laboratory skills currently performed   in research. By the analysis of research papers they should be able to identify the main steps in pathways that are altered and the mechanism of regulation.

Working method

Presencial

Pre-requirements (prior knowledge) and co-requirements (common knowledge)

Not applicable

Program

1. Sources of cell energy: carbohydrates and lipids


2. The metabolism of glucose: synthesis and degradation of glycogen


3. Alcoholic and lactic fermentation


4. Krebs cycle and respiratory chain: ATP synthesis


5. Fatty acids and cholesterol synthesis


6. The fatty acids as source of ATP


7. Cholesterol metabolism


8. Regulation of metabolic pathways


9. Metabolic integration


10. Molecular signaling


11. Nitrogen metabolism: aminoacids e nucleotides


12. Discussion of metabolic situations


13. Molecular stress response

Mandatory literature

Nelson David L.; Lehninger principles of biochemistry. ISBN: 0-7167-4339-6
Stryer Lubert; Biochemistry. ISBN: 0-7167-0174-X

Comments from the literature

not applicable

Teaching methods and learning activities

The course curriculum is designed aiming at providing the required knowledge that leads to understand how the cell function in an integrated form. Besides the lectures , students are required to discuss research papers to use the acquires knowledge in the analysis of experimental data. The lectures follow a usual pattern with the aid of power point presentations followed by questions. Students are attending practical laboratory sessions designed to illustrate the main points of the theoretical course.

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Designation	Weight (%)
Exame	50,00
Trabalho laboratorial	25,00
Trabalho prático ou de projeto	25,00
Total:	100,00

Amount of time allocated to each course unit

Designation	Time (hours)
Apresentação/discussão de um trabalho científico	6,00
Total:	6,00

Eligibility for exams

3/4 of laboratory sessions.

Calculation formula of final grade

FM = PP x 0.25 + EM x 0,5 + LM x 0,25

FM   = final mark
PP = paper presenation mark
EM = examn  mark
LM = laboratory assesment mark

Examinations or Special Assignments

Not applicable

Internship work/project

Not applicable

Special assessment (TE, DA, ...)

not applicable

Classification improvement

by registration to a new examination

Observations

Not applicable