Cellular Biology

Code:

EBE0202

Acronym:

BIOCEL

Keywords
Classification	Keyword
OFICIAL	Basic Sciences

Instance: 2016/2017 - 2S

Active?	Yes
Responsible unit:	Microscopy
Course/CS Responsible:	Master in Bioengineering

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MIB	92	Syllabus	1	-	6	70	162

Teaching language

Portuguese

Objectives

Students should be aware of the diversity of cell types and should obtain theoretical knowledge on the morphology, functional aspects and biogenesis of cytoplasmic and nuclear structures so as to understand the functional dynamics of cells. Students must also acquire basic knowledge on histology and microscopy techniques. .

Learning outcomes and competences

Students are expected to develop their study abilities and to acquire fundamental knowledge enabling them to follow future developments of science in the area of Cell Biology. The development of observation skills is another goal of the curricular unit and students should be able to identify the main types of cells and tissues in histological sections and recognise the various cellular structures in electron microscopy images

Working method

Presencial

Program

Characterisation and diversity of prokaryotic and eukaryotic cells. Microscopes, microscopy techniques and other study methods in cell biology. Chemical components of the cell: carbohydrates, lipids, proteins and nucleic acids. DNA replication and transcription, RNA splicing, ribosomes and protein synthesis. Composition, structure and functions of biological membranes. The glycocalyx. Cytoskeleton and related structures: microtubules (cilia and flagella), microfilaments and intermediate filaments. Cell motility. Nucleus: nuclear envelope and nuclear pore transport, chromatin and chromosomes, the nucleolus and the synthesis of ribosomal RNA. Cell cycle and division: mitosis, meiosis and cytokinesis. Ultrastructure, functions and biogenesis of cytoplasmic organelles: endoplasmic reticulum, Golgi apparatus, lysosomes, mitochondria, chloroplasts and peroxisomes. Extracellular matrix. Intercellular junctions. Gametes and fertilization. Apoptosis. Basics of histology.

Mandatory literature

Alberts Bruce; Molecular biology of the cell. ISBN: 978-0-8153-4105-5
Azevedo C and Sunkel CE ; Biologia Celular e Molecular, LIDEL, 2012
Cooper GM, Hausman RE ; The Cell: A Molecular Approach, 2013. ISBN: Sixth Edition
Gartner LP, Hiatt JL ; Color Textbook of Histology, 2007
Young B, Woodford P, O'Dowd G ; Wheater's Functional Histology: A Text and Colour Atlas, 2013

Teaching methods and learning activities

Explanation of theoretical contents are supported by audiovisual tools. Laboratorial classes dedicated to microscopy techniques, observation of histological sections stained by diverse light microscopy techniques and observation of transmission electron microscopy images.

keywords

Natural sciences > Biological sciences > Biology > Cell biology
Natural sciences > Biological sciences > Biology > Molecular biology
Natural sciences > Biological sciences > Biology > Histology

Evaluation Type

Evaluation with final exam

Assessment Components

Designation	Weight (%)
Exame	100,00
Total:	100,00

Amount of time allocated to each course unit

Designation	Time (hours)
Estudo autónomo	0,00
Frequência das aulas	0,00
Total:	0,00

Calculation formula of final grade

Final classification is equal to the exam classification