Name: | Helder Rui Cardoso da Cruz |
Sigla: | HRCC |
Estado: | Active |
R-000-KFH | |
0000-0001-5191-3828 | |
6B15-A32E-33A9 | |
N-3486-2019 | |
35602600800 |
Email Institucional: | hcruz |
Extensão Telefónica: | 26746 |
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Cardoso-Cruz H*, Laranjeira I, Monteiro C, Galhardo V (2022) Altered prefrontal-striatal theta-band oscillatory dynamics underlie working memory deficits in neuropathic pain rats. European Journal of Pain 26:1546-1568.
Cardoso-Cruz H*, Paiva P, Monteiro C, Galhardo V (2019) Selective optogenetic inhibition of medial prefrontal glutamatergic neurons reverses working memory deficits induced by neuropathic pain. PAIN 160:805-823.
Cardoso-Cruz H*, Paiva P, Monteiro C, Galhardo V (2019) Bidirectional optogenetic modulation of prefrontal-hippocampal connectivity in pain-related working memory deficits. Scientific Reports 9:10980.
Monteiro C, Cardoso-Cruz H, Galhardo V. (2019) Animal models of congenital hypoalgesia: Untapped potential for assessing pain-related plasticity. Neuroscience Letters 702:51-60. (Review)
Cardoso-Cruz H*, Dourado M, Monteiro C, Galhardo V (2018) Blockade of dopamine D2 receptors disrupts intrahippocampal connectivity and enhances pain-related working memory deficits in neuropathic pain rats. European Journal of Pain 22:1002-1015.
Monteiro C, Cardoso-Cruz H, Matos M, Dourado M, Lima D, Galhardo V* (2016) Increased fronto-hippocampal connectivity in the Prrxl1 knockout mouse model of congenital hypoalgesia. PAIN 157:2045-2056.
Dourado M, Cardoso-Cruz H, Monteiro C, Galhardo V* (2016) Effect of Motor Impairment on Analgesic Efficacy of Dopamine D2/3 Receptors in a Rat Model of Neuropathy. Journal of Experimental Neuroscience 10:51-7.
Cardoso-Cruz H, Dourado M, Monteiro C, Matos MR, Galhardo V* (2014) Activation of dopaminergic D2/D3 receptors modulates dorsoventral connectivity in the hippocampus and reverses the impairment of working memory after nerve injury. The Journal of Neuroscience 34:5861-5873.
Cardoso-Cruz H, Sousa M, Vieira JB, Lima D, Galhardo V* (2013) Prefrontal cortex and mediodorsal thalamus reduced connectivity is associated with spatial working memory impairment in rats with inflammatory pain. PAIN 154:2397-2406.
Cardoso-Cruz H, Lima D, Galhardo V* (2013) Impaired spatial memory performance in a rat model of neuropathic pain is associated with reduced hippocampus-prefrontal cortex connectivity. The journal of Neuroscience 33:2465-2480.
Cardoso-Cruz H, Lima D, Galhardo V* (2011) Instability of spatial encoding by CA1 hippocampal place cells after peripheral nerve injury. European Journal of Neuroscience 33:2255-2264.
Cardoso-Cruz H, Sameshima K, Lima D, Galhardo V* (2011) Dynamics of Circadian Thalamocortical Flow of Information during a Peripheral Neuropathic Pain Condition. Frontiers in Integrative Neuroscience 5:43.
Silva A, Cardoso-Cruz H, Silva F, Galhardo V, Antunes L* (2010) Comparison of anesthetic depth indexes based on thalamocortical local field potentials in rats. Anesthesiology 112:355-363.
Marques AP, Cruz HR, Coutinho OP, Reis RL* (2005) Effect of starch-based biomaterials on the in vitro proliferation and viability of osteoblast-like cells. Journal of Materials Science: Materials in Medicine 16(9):833-42.
Selected research projects:
2023 - to date; FCT: 10.54499/2022.00128.CEECIND/CP1735/CT0019; "Shed light on comorbid pain-related Lateral Habenula network dysfunctions during cognitive motifs"; (Salary Grant, 375 k¤)
2023- to date; PAIN ADDICT - Dopaminergic circuits underlying habit formation and addiction in animal models of chronic pain (Project Grant, 249 k¤; Research Team core member).
2019-2023; FCT: 10.54499/DL/2016/CP1355/CT0015; "Optogenetic dissection of the prefrontal cortex networks to reverse pain-related cognitive dysfunctions"; (Salary Grant, 177 k¤).
2018-2022; FCT: PTDC/MED-NEU/28181/2017; "MEMORYSTIM - Optogenetic modulation of prefrontal GABAergic and dopaminergic signaling to reverse pain-related cognitive deficits" (Project Grant, 229 k¤; Principal Researcher).
2018-2021; FCT: PTDC/MED-NEU/28498/2017; "OPTORISK - Reward signals codification in neural populations of dopaminergic circuitry: optogenetic study of the neural correlates of decision and expectance"; (Project Grant, 238 k¤; Research Team core member).
Guest Editor
Diagnostics - Special Issue: "Progress in Chronic Pain: Bridging Basic and Clinical Research"
Deadline: 31 December 2025
https://www.mdpi.com/journal/diagnostics/special_issues/IOO261P537