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Project: PHC PESSOA - Portugal-France Bilateral Cooperation

Project name: MitoTARGET4AD - MitoTARGET4AD: Improving Nature for a Novel Disruptive Treatment for Alzheimer’s Disease
Project code: PHC PESSOA - Portugal-France Bilateral Cooperation
Proposing institution/Lead promoter/Coordinating entity: Faculdade de Ciências da Universidade do Porto
Partner(s)/Co-promoter(s)/Participating institution(s): UNIVERSITÉ DE MONTPELLIER
Start date: 2023-01-01
Completion date: 2024-12-31
Eligible Cost of the Project
Total Eligible Cost: 4.000,00 EUR
Eligible Cost in the University of Porto: 4.000,00 EUR
Faculdade de Ciências da Universidade do Porto: 4.000,00 EUR
Objectives, activities and expected/achieved results
Within this bilateral cooperation, we will evaluate the drug-like properties of MTAs and validate their pharmacological profiles and efficacy in a mouse model, namely by the intracerebroventricular administration of
oligomerized Aß25-35 peptide, which has a predictive value towards transgenic mouse models and towards the developability of compounds at the clinical stage. Altogether, the data obtained will set up the first step of proof-of
concept.
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