Impairment of EQ-5D-5L Domains According to Allergic Rhinitis and Asthma Control: A MASK-air Real-World Study

• Tipo: Artigo em Revista Científica Internacional
• Data: 2023

Autores

Sousa Pinto, B (Autor) FMUP; Louis, G (Autor) Outra; Rodrigues, J (Autor) Outra; Giuliano, AFM (Autor) Outra; Baiardini, I (Autor) Outra; Braido, F (Autor) Outra; Czarlewski, W (Autor) Outra; Bedbrook, A (Autor) Outra; Haahtela, T (Autor) Outra; Valiulis, A (Autor) Outra; Brussino, L (Autor) Outra; Cecchi, L (Autor) Outra; Cruz, AA (Autor) Outra; Gemicioglu, B (Autor) Outra; Fokkens, WJ (Autor) Outra; Ivancevich, JC (Autor) Outra; Klimek, L (Autor) Outra; Kraxner, H (Autor) Outra; Kuna, P (Autor) Outra; Kupczyk, M (Autor) Outra; Kvedariene, V (Autor) Outra; Larenas Linnemann, D (Autor) Outra; Louis, R (Autor) Outra; Nadif, R (Autor) Outra; Niedoszytko, M (Autor) Outra; Okamoto, Y (Autor) Outra; Ollert, M (Autor) Outra; Papadopoulos, NG (Autor) Outra; Patella, V (Autor) Outra; Pawankar, R (Autor) Outra; Pham Thi, N (Autor) Outra; Pfaar, O (Autor) Outra; Regateiro, FS (Autor) Outra; Roche, N (Autor) Outra; Rouadi, PW (Autor) Outra; Samolinski, B (Autor) Outra; Sastre, J (Autor) Outra; Savoure, M (Autor) Outra; Scichilone, N (Autor) Outra; Sheikh, A (Autor) Outra; Taborda Barata, L (Autor) Outra; ToPPila Salmi, S (Autor) Outra; Yorgancioglu, A (Autor) Outra; Zidarn, M (Autor) Outra; Anto, JM (Autor) Outra; Zuberbier, T (Autor) Outra; Canonica, GW (Autor) Outra; Ventura, MT (Autor) Outra; Fonseca, J (Autor) FMUP; Petre, B (Autor) Outra; Bousquet, J (Autor) Outra

Revista

Título: Journal of Allergy and Clinical Immunology: In Practice

Vol. 11

Página Inicial: 3742

ISSN: 2213-2198

Editora: Elsevier

Indexação

ISI Web of Knowledge - 7 Citações

Scopus - 7 Citações

Outras Informações

ID Authenticus: P-00Y-W0P

DOI: 10.1016/j.jaip.2023.08.006

Abstract (EN): BACKGROUND: EQ-5D-5L (EuroQOL, 5 Domains, 5 Levels) is a widely used health-related quality-of-life instrument, comprising 5 domains. However, it is not known how each domain is impacted by rhinitis or asthma control. OBJECTIVE: To assess the association between rhinitis or asthma control and the different EQ-5D-5L domains using data from the MASK-air mHealth app. METHODS: In this cross-sectional study, we assessed data from all MASK-air users (2015-2021; 24 countries). For the levels of each EQ-5D-5L domain, we assessed rhinitis and asthma visual analog scales (VASs) and the combined symptom-medication score (CSMS). We built ordinal multivariable models assessing the adjusted association between VAS/CSMS values and the levels of each EQ-5D-5L domain. Finally, we compared EQ-5D-5L data from users with rhinitis and self-reported asthma with data from users with rhinitis alone. RESULTS: We assessed 5354 days from 3092 users. We observed an association between worse control of rhinitis or asthma (higher VASs and CSMS) and worse EQ-5D-5L levels. In multivariable models, all VASs and the CSMS were associated with higher levels of pain/discomfort and daily activities. For anxiety/depression, the association was mostly observed for rhinitis-related tools (VAS nose, VAS global, and CSMS), although the presence of self-reported asthma was also associated with worse anxiety/depression. Worse mobility (walking around) was particularly associated with VAS asthma and with the presence of asthma.CONCLUSIONS: A worse rhinitis control and a worse asthma control are associated with higher EQ-5D-5L levels, particularly regarding pain/discomfort and activity impairment. Worse rhinitis control is associated with worse anxiety/depression, and poor asthma control with worse mobility. (c) 2023 American Academy of Allergy, Asthma & Immunology (J Allergy Clin Immunol Pract 2023;11:3742-51)

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 19