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Developments Towards Regioselective Synthesis of 1,2-Disubstituted Benzimidazoles

Title
Developments Towards Regioselective Synthesis of 1,2-Disubstituted Benzimidazoles
Type
Another Publication in an International Scientific Journal
Year
2011
Authors
Luisa C R Carvalho
(Author)
Other
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Eduarda Fernandes
(Author)
FFUP
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Manuel M B Marques
(Author)
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Journal
Vol. 17
Pages: 12544-12555
ISSN: 0947-6539
Publisher: Wiley-Blackwell
Scientific classification
FOS: Natural sciences > Chemical sciences
Other information
Authenticus ID: P-002-JPS
Abstract (EN): 1,2-Disubstituted benzimidazoles play an important role in several areas and particularly as drug discovery targets. Herein, several methods to assemble these structures are reviewed, from the classical approaches to the more recently developed metal-catalyzed intramolecular amination process, the cascade arylamination/condensation reaction and polymer-supported benzimidazole assembly under microwave conditions.
Language: English
Type (Professor's evaluation): Scientific
Contact: mmbmarques@dq.fct.unl.pt
No. of pages: 12
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