Bromelain-loaded nanoparticles: A comprehensive review of the state of the art

• Type: Article in International Scientific Journal
• Date: 2018

Authors

Ataide, JA (Author) Other; Gérios, EF (Author) Other; Mazzola, PG (Author) Other; Souto, EB (Author) Other

Journal

Title: Advances in Colloid and Interface Science

Vol. 254

Pages: 48-55

ISSN: 0001-8686

Publisher: Elsevier

Indexing

Scopus - 10 Citations

Other information

Authenticus ID: P-00N-V1Y

DOI: 10.1016/j.cis.2018.03.006

Abstract (EN): Stem bromelain is a common available cysteine protease derived from pineapple (Ananas comosus L.). Bromelain finds widespread applications in several areas, such as medicine, health, food, and cosmetics, and its strong proteolytic activity supports its future application in many additional fields. However, most proteins and/or enzymes are fragile, leading to important considerations about increase storage and operational stability to enable their practical application. In this scenario, the use of nanoparticles to deliver proteins is increasing exponentially, given that these systems are capable of enhance active's stability, solubility and permeability, and decrease toxicity. In the pharmaceutical nanotechnology field, bromelain has played different roles and thus this paper aims to review the available literature for the use of nanoparticles and bromelain. © 2017

Language: English

Type (Professor's evaluation): Scientific