Analytical methodology to screen UV-filters and synthetic musk compounds in market tomatoes

• Type: Article in International Scientific Journal
• Date: 2020

Authors

Sara Ramos (Author) Other; Vera Homem (Author) FEUP; Lúcia Silveira Santos (Author) FEUP

Journal

Title: Chemosphere

Vol. 238 No. Article number 124605

Pages: 1-10

ISSN: 0045-6535

Publisher: Elsevier

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ISI Web of Knowledge - 17 Citations

Scopus - 18 Citations

ScienceDirect (Elsevier)

Associated Projects

AGRONAUT - Estudo do impacto agronómico da utilização de lamas de depuração através de uma perspectiva de exposição

LEPABE-2-ECO-INNOVATION - LEPABE-2-ECO-INNOVATION

LEPABE - Projeto Estratégico do LEPABE - Laboratório de Engenharia de Processos, Ambiente, Biotecnologia e Energia

Other information

Authenticus ID: P-00Q-YG4

DOI: 10.1016/j.chemosphere.2019.124605

Abstract (EN): A Quick, Easy, Cheap, Effective, Rugged and Safe (QuEChERS) methodology followed by gas chromatography-tandem mass spectrometry (GC-MS/MS) analysis was developed to extract thirteen synthetic musk compounds (SMCs: cashmeran, celestolide, phantolide, traseolide, galaxolide, tonalide, musk ambrette, musk xylene, musk ketone, musk tibetene, musk moskene, ethylene brassylate and exaltolide) and six ultraviolet-filters (UVFs: 2-ethylhexyl 4-dimethylaminobenzoate, 3-(4′-methylbenzylidene) camphor, 2-ethylhexyl 4-methoxycinnamate, 2-ethylhexyl 2-cyano-3,3-diphenylacrylate, benzophenone and drometrizole trisiloxane) from tomatoes. The proposed methodology was optimized: 2 g of freeze-dried tomato was extracted with 4 mL of water and 10 mL of ethyl acetate, adding 6 g of MgSO4 and 1.5 g of NaCl, then a dispersive solid-phase extraction was performed using 3 g of MgSO4, 300 mg of primary-secondary amino adsorbent (PSA) and 300 mg of octadecyl-silica (C18). Validation delivered recoveries between 81 (celestolide) and 119% (musk tibetene), with relative standard deviations <10%. The instrumental limit of detection varied from 0.02 (2-ethylhexyl 4-methoxycinnamate) to 3.00 pg (exaltolide and musk xylene). Regarding the method quantification limits, it ranged between 0.4 (celestolide) and 47.9 ng g−1 dw (exaltolide). The method was applied to different varieties of tomatoes (Solanum lycopersicum), revealing UVFs and SMCs between 1 and 210 ng g−1 dw. Higher concentrations were found for benzophenone (29–210 ng g−1 dw) and galaxolide (9–53 ng g−1 dw). The risk associated to the ingestion of contaminated tomatoes has also been estimated, showing that a potential health risk is unlikely. © 2019 Elsevier Ltd

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 10